Recorded sessions on demand will be available 24 hours after the session ends

Abstract Body

Neonatal seizure have various causes. The most common etiology is acute brain injury caused by perinatal asphyxia, stroke or infection. Nevertheless, genetic epileptic encephalopathies may have various genetic causes. These causes comprise channelopathies, metabolic diseases and malformations of cortical development (i.e. SCN2A associated mutations, vitamin-responsive disorders and structural abnormalities in neurocutaneos syndromes, respectively). Timely recognition of these etiologies is mandatory, as for some causes, personalized treatment strategies are available. In the present course, causes of neonatal seizures are discussed. Special considerations on genetic etiologies will be made with respect to a diagnostic algorithm and current available treatment options as specific antiepileptic drug therapy, vitamin supplementation and epilepsy surgery.