B. Putra (Blitar, Indonesia)
Author Of 2 Presentations
145P - The Potential Benefits of Internet-based Cognitive Behavioural Therapy for Improving Psychosocial Aspects, Sexual Functioning, And Treatment-induced Menopausal Symptoms Among Breast Cancer Survivors: Systematic Review and Meta-analysis
Abstract
Background
Breast cancer (BC) survivors must continue their treatments during the pandemic, include the psychotherapy, although limited due to the COVID-19 pandemic. Previous studies suggested inconclusive promising results of internet-based cognitive behavioural (iCBT) for breast cancer survivors. This study aims to compare the efficacies between iCBT and usual care (UC) for improving psychosocial aspects, sexual functioning, and treatment-induced menopausal symptoms (TIMS) among breast cancer survivors.
Methods
We did comprehensive literature searching in several online databases to include all relevant studies from January 2000 until January 2021 then followed PRISMA guideline. We included all randomized controlled trials (RCTs) that compared the efficacies between iCBT and UC in BC survivors then accessed the changes of psychosocial aspects, sexual functioning, and TIMS. We used the Cochrane Risk-of-bias (RoB 2) tool for accessing bias risks. We performed analysis to provide standard mean difference (SMD) with 95% confidence interval (CI) using random-effect heterogeneity test.
Results
We included 5 RCTs met our inclusion criteria. The iCBT shows non-inferiority compared with the UC group for improving seven psychosocial aspects in BC survivors. The iCBT improves sexual pleasure (SMD=0.26, 95% CI 0.04–0.48, p=0.02, I2=0%) and discomfort during sex (SMD=−0.40, 95% CI -0.79 to -0.01, p=0.04, I2=54%) significantly, but not statistically significant in improving intercourse frequency (SMD=0.15, 95% CI -0.49 to 0.80, p=0.65, I2=88%). The iCBT also shows significant improvements of sleep quality (SMD=−0.86, 95% CI -1.28 to -0.44, p<0.0001, I2=83%), hot flush frequency (SMD=−0.5, 95% CI -0.70 to -0.29, p<0.00001, I2=0%), night sweet frequency (SMD=−0.75, 95% CI -1.24 to -0.26, p=0.003, I2=81%), and the overall levels of TIMS (SMD=0.53, 95% CI 0.31–0.75, p<0.00001, I2=0%).
Conclusions
The iCBT showed potential benefits for improving psychosocial aspects, sexual functioning, and TIMS among BC survivors compared with the UC. However, further studies are needed to establish the efficacies.
Legal entity responsible for the study
The authors.
Funding
Has not received any funding.
Disclosure
All authors have declared no conflicts of interest.
150P - Expanding The Potential Benefits of Cognitive Behavioural Therapy for Insomnia in Improving Psychological Functioning And Quality of Life Among Breast Cancer Survivors with Insomnia: A Meta-analysis of Randomized Controlled Trials
Abstract
Background
Insomnia is a serious problem whose prevalence about 30-60% of breast cancer (BC) survivors that can affect their treatments and daily living. Previous studies showed that cognitive behavioural therapy for insomnia (CBT-I) had established efficacies for improving insomnia, while the psychological functioning and quality of life (QoL) outcomes were still inconclusive. This study aims to compare the efficacies between CBT-I and standard care (SC) for improving psychological functioning and QoL among breast cancer survivors with insomnia.
Methods
We searched literature comprehensively through several online databases to include all relevant studies from 2000 until 2020. We followed PRISMA guideline for conducting this study. We included all randomized controlled trials (RCTs) that compared the efficacies between CBT-I and SC in BC survivors then accessed the changes of anxiety, depression, fatigue, QoL, and sleep dysfunction belief. Bias risk was accessed by using the Cochrane Risk-of-bias (RoB 2) tool. Analysis was conducted to provide standard mean difference (SMD) with 95% confidence interval (CI) using random-effect heterogeneity test.
Results
We included 6 RCTs met our inclusion criteria. The CBT-I group shows significant improvements of anxiety (SMD = -0.22, 95% CI -0.42 to -0.02, p=0.03, I2=0%), depression (SMD = -1.91, 95% CI -3.61 to -0.20, p=0.03, I2=98%), fatigue (SMD = 0.35, 95% CI 0.13 to 0.57, p=0.002, I2=42%), and sleep dysfunction belief (SMD = -0.31, 95% CI -0.57 to -0.04, p=0.02, I2=0%). The CBT-I also improves the QoL among BC survivors compared with the SC group although not statistically significant (SMD = 0.19, 95% CI -0.01 to 0.39, p=0.07, I2=0%).
Conclusions
The CBT-I provided potential benefits for improving psychosocial functioning and QoL among BC survivors with insomnia. Nevertheless, further studies are needed to establish the efficacies.
Legal entity responsible for the study
The authors.
Funding
Has not received any funding.
Disclosure
All authors have declared no conflicts of interest.
Presenter Of 2 Presentations
145P - The Potential Benefits of Internet-based Cognitive Behavioural Therapy for Improving Psychosocial Aspects, Sexual Functioning, And Treatment-induced Menopausal Symptoms Among Breast Cancer Survivors: Systematic Review and Meta-analysis
Abstract
Background
Breast cancer (BC) survivors must continue their treatments during the pandemic, include the psychotherapy, although limited due to the COVID-19 pandemic. Previous studies suggested inconclusive promising results of internet-based cognitive behavioural (iCBT) for breast cancer survivors. This study aims to compare the efficacies between iCBT and usual care (UC) for improving psychosocial aspects, sexual functioning, and treatment-induced menopausal symptoms (TIMS) among breast cancer survivors.
Methods
We did comprehensive literature searching in several online databases to include all relevant studies from January 2000 until January 2021 then followed PRISMA guideline. We included all randomized controlled trials (RCTs) that compared the efficacies between iCBT and UC in BC survivors then accessed the changes of psychosocial aspects, sexual functioning, and TIMS. We used the Cochrane Risk-of-bias (RoB 2) tool for accessing bias risks. We performed analysis to provide standard mean difference (SMD) with 95% confidence interval (CI) using random-effect heterogeneity test.
Results
We included 5 RCTs met our inclusion criteria. The iCBT shows non-inferiority compared with the UC group for improving seven psychosocial aspects in BC survivors. The iCBT improves sexual pleasure (SMD=0.26, 95% CI 0.04–0.48, p=0.02, I2=0%) and discomfort during sex (SMD=−0.40, 95% CI -0.79 to -0.01, p=0.04, I2=54%) significantly, but not statistically significant in improving intercourse frequency (SMD=0.15, 95% CI -0.49 to 0.80, p=0.65, I2=88%). The iCBT also shows significant improvements of sleep quality (SMD=−0.86, 95% CI -1.28 to -0.44, p<0.0001, I2=83%), hot flush frequency (SMD=−0.5, 95% CI -0.70 to -0.29, p<0.00001, I2=0%), night sweet frequency (SMD=−0.75, 95% CI -1.24 to -0.26, p=0.003, I2=81%), and the overall levels of TIMS (SMD=0.53, 95% CI 0.31–0.75, p<0.00001, I2=0%).
Conclusions
The iCBT showed potential benefits for improving psychosocial aspects, sexual functioning, and TIMS among BC survivors compared with the UC. However, further studies are needed to establish the efficacies.
Legal entity responsible for the study
The authors.
Funding
Has not received any funding.
Disclosure
All authors have declared no conflicts of interest.
150P - Expanding The Potential Benefits of Cognitive Behavioural Therapy for Insomnia in Improving Psychological Functioning And Quality of Life Among Breast Cancer Survivors with Insomnia: A Meta-analysis of Randomized Controlled Trials
Abstract
Background
Insomnia is a serious problem whose prevalence about 30-60% of breast cancer (BC) survivors that can affect their treatments and daily living. Previous studies showed that cognitive behavioural therapy for insomnia (CBT-I) had established efficacies for improving insomnia, while the psychological functioning and quality of life (QoL) outcomes were still inconclusive. This study aims to compare the efficacies between CBT-I and standard care (SC) for improving psychological functioning and QoL among breast cancer survivors with insomnia.
Methods
We searched literature comprehensively through several online databases to include all relevant studies from 2000 until 2020. We followed PRISMA guideline for conducting this study. We included all randomized controlled trials (RCTs) that compared the efficacies between CBT-I and SC in BC survivors then accessed the changes of anxiety, depression, fatigue, QoL, and sleep dysfunction belief. Bias risk was accessed by using the Cochrane Risk-of-bias (RoB 2) tool. Analysis was conducted to provide standard mean difference (SMD) with 95% confidence interval (CI) using random-effect heterogeneity test.
Results
We included 6 RCTs met our inclusion criteria. The CBT-I group shows significant improvements of anxiety (SMD = -0.22, 95% CI -0.42 to -0.02, p=0.03, I2=0%), depression (SMD = -1.91, 95% CI -3.61 to -0.20, p=0.03, I2=98%), fatigue (SMD = 0.35, 95% CI 0.13 to 0.57, p=0.002, I2=42%), and sleep dysfunction belief (SMD = -0.31, 95% CI -0.57 to -0.04, p=0.02, I2=0%). The CBT-I also improves the QoL among BC survivors compared with the SC group although not statistically significant (SMD = 0.19, 95% CI -0.01 to 0.39, p=0.07, I2=0%).
Conclusions
The CBT-I provided potential benefits for improving psychosocial functioning and QoL among BC survivors with insomnia. Nevertheless, further studies are needed to establish the efficacies.
Legal entity responsible for the study
The authors.
Funding
Has not received any funding.
Disclosure
All authors have declared no conflicts of interest.