Mohammad Adawi, Israel

Padeh and Ziv Hospitals, , Azrieli Faculty of Medicine, Bar-Ilan University Rheumatology
I was born in Israel in the city of Nazareth on 18/2/61. I am married to Khitam, who is a medical laborant and the father of three daughters who are all medical students. In 1980, I graduated from a high school in the village of Tura’n and in 1990; I graduated in medicine from the Technion institute. In 1993, I completed an internship in internal medicine at the Valley Medical Center and in 1995; I completed an internship in rheumatology at Rambam Medical Center. Until 2015, I served as Deputy Director of the Rheumatology Unit at Valley Medical Center. For the past 6 years I have been the director of the Rheumatology Unit at Poria & Safed medical center a. I am a senior lecturer in the Azrieli Faculty of Medicine, Bar-Ilan University, Israel (I applied for the rank of Clinical Associate Professor)

Presenter of 2 Presentations

 Conference Calendar

THE IMPACT OF JET-LAG ON PSORIATIC AND PSORIATIC ARTHRITIS PATIENTS DISEASE SEVERITY SCORES: DOES IT MATTER?

Session Name
PS12 -DIET, ENVIRONMENT, STRESS AND AUTOIMMUNITY
Session Type
PARALLEL SESSIONS
Date
29.05.2021, Saturday
Session Time
13:30 - 15:30
Room
HALL F
Lecture Time
14:40 - 14:50
Presenter
Session Icon
Pre Recorded

Abstract

Background and Aims

Jet-lag may affect air-travellers crossing at least two time-zones. It occurs when the human biological rhythms are out of synch with respect to the day-night cycle at the country destination. Its effect in psoriasis is missing. We aimed to evaluate the effect of Jet-lag in psoriatic patients' management.

Methods

Patients that underwent a flight: patients who experienced jet-lag were compared to patients who did not experience jet-lag. Before the flight, a dermatologist recorded clinical and demographical data with particular attention to Psoriasis Area Severity Index (PASI) and Disease Activity in Psoriatic Arthritis (DAPSA). Patients performed Self-Administered Psoriasis Area Severity Index (SAPASI), the Dermatology Life Quality Index (DLQI) and the pruritus Visual Analog Scale (VAS) scores. After the flight, patients completed the SAPASI, DLQI and pruritus-VAS scores.

Results

The sample recruited comprised of 70 psoriatic patients aged 42.4 ± 9.7 years (median 42.5 years). Thirty (42.9%) were males, mean BMI was 25.5 ± 2.2 kg/m2. Average disease duration was 15.2 ± 7.1 years, and 20 (28.6%) subjects had developed PsA. Average hours of flight were 5.4 ± 3.5 (median 3.5 h), with 34 (48.6%) subjects reporting jet-lag. At the multivariate regression analysis, the change in the SAPASI score resulted correlated with jet-lag (regression coefficient 1.63, p = .0092), as well the change in the DLQI score (regression coefficient = 1.73, p = .0009), but no change on the pruritus VAS scale was found.

Conclusions

This study suggests that jet-lag may influence disease severity and DLQI scores, but not itch in psoriatic patients.

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THE IMPACT OF GENDER ON THE RISK OF CARDIOVASCULAR EVENTS IN PATIENTS WITH RHEUMATOID ARTHRITIS

Session Name
PS41 - GENETICS AND EPIGENETICS IN AUTOIMMUNITY
Session Type
PARALLEL SESSIONS
Date
31.05.2021, Monday
Session Time
10:00 - 12:00
Room
HALL B
Lecture Time
11:10 - 11:20
Presenter
Session Icon
Pre Recorded

Abstract

Background and Aims

Rheumatoid Arthritis (RA) is a chronic inflammatory disease, affecting women more than men, with a more aggressive course in women.

Methods

A prospective study that recruited 58 patients (46 women aged 56 ± 12 years) with active long-standing RA disease (>12 months). Our goals were to measure their endothelial function, part of the cardiovascular risk assessment. The Brachial Artery method measured endothelial function (the flow mediated percent change [FMD percentage] of the brachial artery diameter). A senior Rheumatologist clinically evaluated all subjects. Mann Whitney rank sum test estimated gender differences among the RA patients.

Results

Median FMD% change for men was -6.07%, while median FMD% change for women was 0.44% (Z = 2.38, P = 0.01). Baseline Brachial artery diameter was larger in men (Z = 2.52, P = 0.01); however, tender joints count and BMI were greater in women (Z=-2.24, P = 0.01; Z=-3.99, P = 0.001), respectively.

Conclusions

Women with RA have significantly better endothelial function than men with RA. It means that even though RA is 3-fold more prevalent in women, women are more protected from atherosclerotic coronary artery disease and cardiac events.

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