Ralph Ziegler, Germany
Pediatric Practice DiabetologiePresenter of 2 Presentations
ACCURACY OF INSULIN DELIVERY IN DURABLE PUMPS
Abstract
Background and Aims
Accuracy of insulin pumps is of current interest, especially with regard to development of closed loop systems. This study evaluated accuracy of the three most recent durable insulin pumps with regard to bolus and basal rate delivery.
Methods
The three durable pumps MiniMed® 670G [670G], t:slim X2 [TS] and mylife™ YpsoPump® [YP] were tested. Experimental testing was based on EN 60601-2-24 which requires a microgravimetric procedure. Basal rates of 0.1 U/h and 1 U/h, and boluses of 0.1 U, 1 U and 10 U were tested in 9 repetitions each. Basal rate delivery was assessed for 72 h evaluating each hour separately. Limits of ±15% from target were applied.
Results
The results are shown in the table.
| Basal rate | Bolus | |||||
| 0.1 U/h | 1 U/h | 0.1 U | 1 U | 10 U | ||
| n | 9 | 9 | 225 | 225 | 108 | |
| 670 G | Mean deviation | 10.6% | 0.1% | 6.0% | 0.3% | -0.8% |
| % of 1-h windows/boluses within ±15% of target | 59% | 99% | 85% | 100% | 100% | |
| TS | Mean deviation | 2.2% | 0.6% | 2.5% | 1.9% | 0.4% |
| % of 1-h windows/boluses within ±15% of target | 63% | 100% | 96% | 100% | 100% | |
| YP | Mean deviation | 4.2% | 1.2% | -2.3% | 1.1% | 0.7% |
| % of 1-h windows/boluses within ±15% of target | 67% | 99% | 88% | 100% | 100% | |
Conclusions
Accuracy of the new pumps fits well into the picture of previously tested durable insulin pumps. In general, accuracy is higher with larger boluses or basal rates.
INSULIN DELIVERY WITH PATCH PUMPS: BOLUS ACCURACY
Abstract
Background and Aims
Patch pumps are a tubeless alternative to conventional durable insulin pumps. Data obtained with two recently released new patch pumps were compared with data previously obtained with an established patch pump.
Methods
Delivery accuracy of the two insulin patch pumps Accu-Chek® Solo micropump [ACS] and A6 TouchCare® pump [A6] was tested in an microgravimetric experiment based on IEC 60601-2-24 for bolus sizes of 0.2 U, 1 U and 10 U. For the already tested Omnipod®, data were only updated testing 0.2 U boluses. Each insulin pump was tested 9 times. One data set comprised 25 (0.2 U and 1 U) or 12 boluses (10 U). A deviation of more than ±15% from target was considered relevant. In addition, delivery speed of a 10 U bolus was assessed.
Results
Bolus accuracy results are shown in the table. Mean delivery time of a 10 U bolus ranged from 04:00 min [ACS] to 06:40 min [A6].
| Bolus volume | 0.2 U | 1 U | 10 U | |
| n | 225 | 225 | 108 | |
| ACS | Mean deviation | -3.3% | 0.3% | 0% |
| % of boluses within ±15% | 88% | 99% | 100% | |
| A6 | Mean deviation | 3.3% | 4.0% | 3.1% |
| % of boluses within ±15% | 40% | 65% | 100% | |
| OmniPod* | Mean deviation | 1.5% | 0.0%* | 0.3%* |
| % of boluses within ±15% | 57% | 77%* | 100%* | |
*results from previous tests
Conclusions
All patch pumps had a mean deviation of less than 5% for all bolus sizes. ACS, however, had a higher percentage of individual boluses within ±15% of target than the two other pumps for the two smaller bolus volumes.