Kelvin M. Leshabari, Tanzania
I-Katch Technology Ltd Clinical ResearchPresenter of 2 Presentations
RELIABILITY AND VALIDITY OF A CHEAP NON-INVASIVE CARDIO-METABOLIC RISKS TOOL AMONG TYPICAL AFRICAN ELDERLY POPULATION: ANALYSIS FROM DAR ES SALAAM IN TANZANIA.
Abstract
Background and Aims
Cardio-metablic risks have been reported to be most prevalent among Americans of African origin. However, there are inconsistencies among studies on the topic from Africans residents of sub-Saharan Africa. This study aimed at assessing the reliability and validity of a new non-invasive cardio-metabolic risk tool for usage among African elderly population.
Methods
A cross-sectional, community-based study was done among Ubungo Msewe residents in Dar es Salaam, Tanzania. Information on weight, height, fasting glycaemia, 2-hours post-prandial glycaemia, resting electrocardiogram, sitting systolic and diastolic blood pressures were performed. Continuous data were summarized using median (IQR) while categorical data were summarized using frequency (%). Generalised linear model was used to ascertain association among variables. Chronbach’s alpha coefficient was used to estimate the reliability index. Variables were assessed for their construct validity. A verbal informed consent was sought from each participant prior to inclusion into the study
Results
We recruited 472 black Africans. Median age was 67 (IQR: 63-71) years. Waist-circumference, female gender, age>65, fasting glycaemia as well as systolic blood pressure were the largest determinant of a cardio-metabolic risk in this study population ( chronbach’s α = .719, p=0.000). Waist -circumference correlated well with BMI ( γ = 0.81, p=.000). Cardio-metabolic risk index increased by a unit for each tenth-increase in systolic BP (p=.02), 3-unit increase in BMI (p=.05), 1.5 unit increase in fasting glycaemic level (p=.000). Majority (68.9%) of study participants had early repolarisation pattern on their resting electrocardiograms.
Conclusions
Non-invasive variables had appreciable reliability and validity in this study population.
PREDICTORS OF CARDIOMETABOLIC RISKS AMONG THE TYPICAL AFRICAN ELDERLY POPULATION: ANALYSIS FROM DAR ES SALAAM, TANZANIA
Abstract
Background and Aims
There is palpable evidence that sub-Saharan Africa is experiencing a demographic transition. Little is known about the predictors of cardiometabolic risk among the elderly segment of African population. This study aimed at assessing predictors of cardiometabolic risks among typical African elders.
Methods
A cross-sectional, community-based study was done among Ubungo Msewe residents in Dar es Salaam, Tanzania. Information on weight, height, fasting glycaemia, 2-hours post-prandial glycaemia, resting electrocardiogram, sitting systolic and diastolic blood pressures were performed. Continuous data were summarized using median (IQR) while categorical data were summarized using frequency (%). Generalised linear model was used to ascertain different association between variables. Chronbach’s alpha coefficient was used to estimate the reliability index. A verbal informed consent was sought from each participant prior to inclusion into the study.
Results
A total of 472 participants were recruited for screening. All participants were black Africans by race. Median age was 67 (IQR: 63-71) years. Male: Female = 1:3.1. There was a significant correlation between gender and blood pressure (γ = 0.52, p=0.000). BMI, 2-hour post-prandial glycaemia, systolic and diastolic blood pressure were significant predictors of cardiometabolic risks (chronbach’s α = 0.77, p=0.000) There was a significant correlation (γ=0.61, p=.02) between age and reported previous adverse cardiovascular events.
Conclusions
BMI, post-prandial glucose stress test and blood pressure significantly predicted the risk of cardiometabolic risks in this study population. Female gender was a significant predictor of blood pressure in this study population.