Here is Dr Genge’s short bio: Dr. Angela Genge has been the Executive Director of the Clinical Research Unit at the Montreal at the Montreal Neurological Institute since 2004. Since 2020, she has also served as Chief Medical Officer for QurAlis and Scientific Director of CATALIS. Her expertise and ground-breaking work in the introduction of innovative therapies in the rare disease space has led her to be a sought-after member of numerous advisory boards for companies developing therapies for these diseases. Clinically, she is the Director of the Neuro ALS clinical program and multidisciplinary clinic, and a neuromuscular neurologist. Throughout her career she has received numerous awards, most recently the 2018 Forbes Norris Award, the DIVA of Distinction Award, and the Governor General Diamond Jubilee Award.

Jean Georges is the Executive Director of Alzheimer Europe, a position he has held since November 1996. His role at Alzheimer Europe includes providing support for the Board, liaising with members or other European umbrella organisations, as well as managing of personnel, financial matters and overall project management of the various projects run by the organisation. Mr Georges has co-authored and contributed to several academic papers within the field of dementia and Alzheimer’s and has served as the Principal Investigator for Alzheimer Europe in projects supported by IMI (Innovative Medicines Initiative) and the European Union’s Research and Innovation Funding Programmes: FP7 and Horizon2020. Throughout his career, Mr Georges has held a number of leadership positions within various European organisations. From 2002-2004 he served as the Secretary General of the European Federation of Neurological Associations. In 2005, he was appointed as one of the two patient representatives on the Management Board of the European Medicines Agency (EMA) a position he held until 2008. In addition, he served as an Executive Committee Member of the European Patients’ Forum. Prior to joining Alzheimer Europe, he served as a Parliamentary Assistant for members of the Luxembourg and European Parliaments and worked as a journalist in the European and International department of the Luxembourg newspaper “Tageblatt”. Mr Georges earned his Bachelor’s degree in English and European literature in 1986 from the University of Essex in the United Kingdom.

I completed my undergraduate studies in biology at Buenos Aires University, Argentina, and conducted my PhD at the same university (2005-​2010), where I characterized a recently identified protein involved in the SUMOylation and hypoxia signaling pathways. Then I moved to ETHZ to learn how to apply systems biology tools, such as targeted proteomics, to characterize the cellular responses to protein misfolding (alpha-Synuclein, Amyloid-beta, Tau), in physiological and pathological contexts (Prof. Paola Picotti lab - ETHZ). In 2016 I moved to Prof. Roland Riek lab to develop novel tools of nuclear magnetic resonance spectroscopy (NMR), and since then I am senior scientist in the same lab. At the Riek lab we apply in-cell NMR to study alpha-Synuclein, Amyloid-beta, Tau and other amyloidogenic proteins involved in neurodegeneration.

Klaus Gerwert is Professor and Head of the Department of Biophysics and Executive Founding Director of the Centre for Protein Diagnostics at Ruhr University Bochum. He is international recognized for detailed studies on reaction mechanisms of membrane proteins. Recently, he invented the Infrared-immuno Sensor for the detection of symptom-free Alzheimer's in blood by a structure biomarker. His professional career includes a Heisenberg fellow at Scripps-Research-Institute in La Jolla and Max-Planck Fellow at SIBS campus in Shanghai.

Curriculum Vitae Hatef Ghasemi Hamidabadi Personal Information: First Name: Hatef Surname: Ghasemi Hamidabadi Date of Birth: 28th of May-1978 Place of Birth: Sari-Iran Gender: Male Marital Status: Married and have one daughter Business Address: Department of Anatomical Sciences School of Medicine Mazandaran University of Medical Sciences (MUMS) Farahabad, Sari, Iran Tel:+98-11 3354 3080 -1(2429) Mob:+98 912 217 6621 Fax:+98 48 4719 1971 Email: hatefdr@gmail.com h.ghasemi@mazums.ac.ir Education: Ph.D in Anatomical Sciences minor in Stem Cell & Germ Cell Biology, embryology lab, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. 2006-2011 (www.tums.ac.ir) Thesis Supervisor: Prof. Aligholi Sobhani Thesis Advisor: Prof Masoud Solimani Thesis Title: Effect of co-culture granulosa cells on differentiation embryonic stem cells to oocyte-like cells Ph.D Thesis Score: 19.85 out of 20 M.Sc in Anatomical Sciences, School of Medicine, from Tarbiat Modares University, Tehran, Iran, 2002-2005 (www.) Thesis Supervisor: Prof. M. Salehnia Thesis Advisor: Prof Z. Batahi Thesis Title: Evaluation of alkaline phosphates activity alteration of mouse endometrium and ovary after hyperstimulation during early pseudopregnancy and implantation time Ph.D Thesis Score: 19.70 out of 20 Presentations: 42nd annual meeting, ISEH society for hematology and stem cells, 22-25 aguset 2013, Viena, Austria. 4th Asian-Pacific International Congress of Anatomis, 7-10 septamber 2005 Kusacasi-Turkey, Turkey. Internatinal Research Award`s Scientific Congress, September 7-9 2005 Royan, Tehran- Iran. 13th World Congress on In Vitro Fertilization Assisted Reproduction & Genetics, May 26-29, 2005 Istanbul, Turkey, Turkey. 8th Congress on Reproductive Biomedicine & 3 th Congress on Stem Cells Biology & Technology, Tehran-Iran Summer 2008..Royan 7th Congress on Reproductive Biomedicine& th Congress on Stem Cells Biology & Technology, Royan, Summer 2007 Royan, Iran 6th Congress on Reproductive Biomedicine& th Congress on Stem Cells Biology & Technology: Summer 2006 Royan, Iran. 8th Congress on Reproductive Biomedicine& 3rd Congress on Stem Cells Biology & Technology: September 5-7 2007 Royan, Tehran- Iran. 11th Congress on Reproductive Biomedicine& 3rd Congress on Stem Cells Biology & Technology: September 2-4 2015 Royan, Tehran- Iran. 5th Annual Meeting of the German Society for Stem Cell Research (GSZGermany, Lubeck, Stem Cell. 5th Annual Meeting of the German Society for Stem Cell Research (GSZ): Bone Morphogenetic Protein 4 role on In vitro Differentiation of Primordial Germ Cells from Mouse Embryonic Stem Cells. Poster Presentation, Germany, Lubeck, Stem Cell. 3rd International and the 6th National Congress on Hematopoietic Stem Cell Transplantatioin and the 1st Regenerative Medicine Congress, 14-16 January, 2016, Tehran-Iran. 4th Basic And Clinical Neuroscience Congress, December 23-25, 2015, Terhran-Iran. 5th Basic And Clinical Neuroscience Congress, December 7-9, 2016, Terhran-Iran. 6th Basic And Clinical Neuroscience Congress, December 20-22, 2017, Terhran-Iran. 10th FENS Forum of Neuroscience, 2-6 July, 2016, Copenhagen, Denmark. 12th Iranian Congress of Anatomical Sciences, May 4-6, 2016, Shahid Beheshti University of Medical Sciences, Tehran-Iran. Workshops: Participation in the workshop of research method in 2005 Participation in the workshop of Scientific writing (advance level ) in 2007 Participation in the workshop of Laser Microdissection in 2006 Optogenetic Workshop in Shahid Beheshti University of Medical Science, 2017 End Not Workshop in Terhan University of Medical Science, 2007 Grants, Awards and Scholarships: Ministry of Health services and Medical education of Iran Scholarship For 6th months research period in The University of Leiden, Leiden, and the Netherlands ($20000). Top university lecturer and researcher in Anatomical sciences. A Plaque for Excellence Presented by the Chancellor of Mazandaran University of Medical Sciences, Sari, Iran (2015). Council for Stem Cell Sciences and Technologies, Tehran, Iran, 2014 ($6000). Council for Stem Cell Sciences and Technologies, Tehran, Iran, 2015 ($6000). Council for Stem Cell Sciences and Technologies, Tehran, Iran, 2015 ($6000). Teaching and Research Experience: Graduate Teaching Associate, Department of Anatomical sciences, School of Medicine, Tarbiat Modares University of Medical Sciences, Tehran, Iran (2005) Graduate Teaching Associate, Department of Anatomical sciences, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran, 2011 (TUMS) Associate Professor of Anatomical sciences and Academic Member of Mazandaran University of Medical Sciences, Sari, Iran, 2011-Present Laboratory Techniques: 1. Light Microscope (LM) 2. Immunohistochemstry (IHC) 3. Immunocytochemstry (ICC) 4. Flowcytometry & FACS analysis 5. RT-PCR 6. Cell Culture 7. Organotype Cell Culture 8. Perfusion 9. Neuronal Specific Staining 10. Electrophysiology 11. Fixation and dissection of human and animal body 12. Optogenetic Teaching Activities: Human Anatomy for Medical students (Thorax, abdomen, pelvis, head, neck, limbs and neuroanatomy) in Mazandaran University of Medical Sciences, Sari, Iran. 2011-Present. Human Anatomy for Dentistry students (Head and neck) in Mazandaran University of Medical Sciences, Sari, Iran. 2011-Present. Lectures to paramedical students (General Anatomy) in Mazandaran University of Medical Sciences, Sari, Iran. 2011-Present. Grants Funded: Evaluation of in vitro differentiation of dental pulp stem cells to neuron-like cells in presence of cerebrospinal fluid and spinal cord repair in adult rat spinal cord injury model Myelin repaire after transplantation of oligoprogenitor cells into demelynation model In vitro transdifferentiation of spermatogonia stem cells into neuron-like cells and transplantation to rat spinal cord injury model Postgraduate Honors Thesis Supervised or Co-supervised: Mahsa Niazi (M.Sc student in Anatomical sciences, Mazandaran University of Medical Sciences, Sari, Iran). Thesis title: Differentiation of mesenchemal human dental pulp stem cells into dopaminergic neurons based on opsin ChR2 and functional evaluation in an animal model of Parkinson’s disease with optogenetics technique. 2016-2017. Sara Haratizadeh (M.Sc student in Anatomical sciences, Mazandaran University of Medical Sciences, Sari, Iran). Thesis title: In vitro differentiation assaessment of dental pulp stem cells into neural-like cells in precence of cerebrospinal fluid. 2015-2016. Ahmad Zeinalzade (Ph.D student in Department of Audiology, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran). Thesis title: The effect of low – level laser on a prevention of noise – induced hearing loss in Guinea pig. 2016-2017. Mino Vardiani (Ph.D student in Anatomical sciences, Shahid Beheshti of Medical Sciences, Tehran, Iran). Thesis title: The study of differentiation of mouse embryonic stem cell into male germ cells utilizing gelatin nanofibrous 3D scaffold and co-culture with Sertoli cells. 2016-2017. Alireza Rahgazar (M.Sc student in Anatomical sciences, Mazandaran University of Medical Sciences, Sari, Iran). Thesis title: Synergistic effect of human chorionic gonadotrophin and Nandrolone Decanoate on histologic and morphometric structure of testis in adult rats. 2014-2015. Masume Behruzi (M.Sc student in Anatomical sciences, Mazandaran University of Medical Sciences, Sari, Iran). Thesis title: Effect of Hydroxyapatite/Fibroin compared to Hydroxy apatite/Gelatin in repair of Rat critical bone defect. 2014-2015. Gazaleh Godarzi (M.Sc student in Anatomical sciences, Mazandaran University of Medical Sciences, Sari, Iran). Thesis title: Evaluation of In vitro effect of cerebrospinal fluid and medium derived from schwann cells on differentiation of bone marrow stromal cells to neuron-like cells and spinal cord repair in rat spinal cord injury. 2013-2014. Somayeh Tadayoni Lehi (M.Sc student in Anatomical sciences, Mazandaran University of Medical Sciences, Sari, Iran). Thesis title: Effect of melatonin and all-trans retinoic acid on maturation, fertilization and embryo development of immature mouse oocytes in vitro. 2013-2014. Maedeh Entezari (M.Sc student in Anatomical sciences, Mazandaran University of Medical Sciences, Sari, Iran). Thesis title: Evaluation of the effect of mouse embryonic fibroblast cells co-culture and its conditioned medium on in vitro maturation of mouse immature oocytes. 2012-2013. Roohollah Ebrahim Pour Malekshah (M.Sc student in Anatomical sciences, Mazandaran University of Medical Sciences, Sari, Iran). Thesis title: Effect of Leptin during in vitro maturation, fertilization and embryonic development of mouse germinal vesicle oocyte. 2011-2012. Professional Services: Curriculum Committee of Mazandaran medical school, Sari, Iran. Set up a Cell Culture Lab at Department of Anatomical sciences, Mazandaran University of Medical Sciences, Sari, Iran. Member of Scientific Committee of Mazandaran University of Medical Sciences, Sari, Iran and medical education for making national Exam from medical students, Sari, Iran. Professional Memberships: Iranian Society of Anatomical Sciences (ISAS). 2007- present. Iranian Neuroscience Society. 2014-present. German Neuroscience Society. 2016-2017. Bibliography: Neuroanatomy with Clinical Points. M. Akbari, Gh. Hassanzadeh, H. Ghasemi, R. Seifali. 2017. Multiple Sclerosis perspectives in Treatment and Pathogenesis. 6th chapter of this book as entitle" Stem Cell Therapy: A Promising Therapeutic Approach for Multiple Sclerosis, published by Codon publications. Freshteh Pourabdolhossein, Hatef Ghasemi Hamidabadi, Maryam Nazm Bojnordi, Sina Mojaverrostami. 2017. General Anatomy. Hatef Ghasemi, Maryam Nazm Bojnordi, Sina Mojaver, Mojtabal Haj Hosseini. 2017. Fertilization. Maryam Nazm Bojnordi, Hatef Ghasemi. 2017. Atlas of Oral Histology & Embryology. Noori Mougahi SMH, Minaii Zanghii B, Choobineh H, Rahmanii M, Ghasemi H, Tack Zareeh, Maleck F. 2011. Publications: 1. Niyazi, Mahsa, Mohammad Ismail Zibaii, Sara Chavoshinezhad, Hatef Ghasemi Hamidabadi, Leila Dargahi, Maryam Nazm Bojnordi, Rafieh Alizadeh et al. "Neurogenic Differentiation of Human Dental Pulp Stem Cells by Optogenetics Stimulation." Journal of Chemical Neuroanatomy (2020): 101821. 2. Darvishi, Marzieh, Hatef Ghasemi Hamidabadi, Sajad Sahab Negah, Ardeshir Moayeri, Taki Tiraihi, Javad Mirnajafi-Zadeh, Ali Jahanbazi Jahan-Abad, and Amir Shojaei. "PuraMatrix hydrogel enhances the expression of motor neuron progenitor marker and improves adhesion and proliferation of motor neuron-like cells." Iranian Journal of Basic Medical Sciences 23, no. 4 (2020): 431. 3. Rezaei, Nourollah, Maryam Nazm Bojnordi, and Hatef Ghasemi Hamidabadi. "Differentiation of Bone Marrow Stromal Stem Cells Seeded on Silk Scaffold to Mature Oligodendrocyte using Cerebrospinal Fluid." Journal of Chemical Neuroanatomy (2020): 101790. 4. Darabi, Shahram, Taki Tiraihi, Maryam Nazm Bojnordi, Hatef Ghasemi Hamidabadi, Nourollah Rezaei, Maria Zahiri, and Rafieh Alizadeh. "Nerve Growth Factor and the Trans-differentiation of Human Dental Pulp Stem Cells Into Cholinergic-like Neurons." Basic and Clinical Neuroscience 10, no. 6 (2019): 7-7. 5. Mahmoudinia, Samira, Ali Niapour, Hatef Ghasemi Hamidabadi, and Mohammad Mazani. "2, 4-D causes oxidative stress induction and apoptosis in human dental pulp stem cells (hDPSCs)." Environmental Science and Pollution Research 26, no. 25 (2019): 26170-26183. 6. Vardiani, Mina, Mazaher Gholipourmalekabadi, Marefat Ghaffari Novin, Morteza Koruji, Hatef Ghasemi Hamidabadi, Maryam Salimi, and Hamid Nazarian. "Three‐dimensional electrospun gelatin scaffold coseeded with embryonic stem cells and sertoli cells: A promising substrate for in vitro coculture system." Journal of cellular biochemistry 120, no. 8 (2019): 12508-12518. 7. Niapour, Ali, Hatef Ghasemi Hamidabadi, Nazila Niapour, Perham Mohammadi, Marzieh Sharifi Pasandi, and Vadoud Malekzadeh. "Pharmacological Notch pathway inhibition leads to cell cycle arrest and stimulates ascl1 and neurogenin2 genes expression in dental pulp stem cells-derived neurospheres." Biotechnology letters 41, no. 6-7 (2019): 873-887. 8. Ghasemi Hamidabadi, Hatef, Maryam Nazm Bojnordi, Hossein Azizi, and Nourollah Rezaei. "The effect of BMP4 on mouse embryonic stem cell proliferation and differentiation into primordial germ cells." Scientific Journal of Kurdistan University of Medical Sciences 24, no. 3 (2019): 110-120. 9. Moghadam, Alireza, Ali Noori-Zadeh, Shahram Darabi, Farzad Rajaei, Hojjat-allah Abbaszadeh, and Hatef Ghasemi Hamidabadi. "Dopaminergic neuroprotection with ginkgolide in 6-hydroxydopamine rat parkinson’s disease model." Journal of Mazandaran University of Medical Sciences 28, no. 170 (2019): 11-21. 10. Alizadeh, Rafieh, Zohreh Bagher, Seyed Kamran Kamrava, Masoumeh Falah, Hatef Ghasemi Hamidabadi, Mahdi Eskandarian Boroujeni, Fatemeh Mohammadi et al. "Differentiation of human mesenchymal stem cells (MSC) to dopaminergic neurons: A comparison between Wharton’s Jelly and olfactory mucosa as sources of MSCs." Journal of chemical neuroanatomy 96 (2019): 126-133. 11. Varmazyar, R., A. Noori-Zadeh, H. A. Abbaszadeh, H. G. Hamidabadi, F. Rajaei, S. Darabi, M. J. Rezaie, M. A. Abdollahifar, F. Zafari, and S. Bakhtiyari. "Neural stem cells neuroprotection by simvastatin via autophagy induction and apoptosis inhibition." Bratislavske lekarske listy 120, no. 10 (2019): 744-751. 12. Bojnordi, Maryam Nazm, Nourollah Rezaei, Zahra Bagheri-Hosseinabadi, Sina Mojaverrostami, Hatef Ghasemi Hamidabadi, Mehrdad Naghikhani, and Mostafa Latifpour. "Cardiogel as an instructive microenvironment for in vitro differentiation of bone marrow-derived mesenchymal stem cells into cardiomyocytes." (2019). Kerman University of Medical Sciences. 13. Azizi, Hossein, Hatef Ghasemi Hamidabadi, and Thomas Skutella. "Differential proliferation effects after Short-Term cultivation of mouse spermatogonial stem cells on different feeder layers." Cell Journal (Yakhteh) 21, no. 2 (2019): 186. 14. Bagheri-Hosseinabadi, Zahra, Hatef Ghasemi Hamidabadi, and Maryam Nazm Bojnordi. "An efficient induction protocol for deriving mature oligodendrocytes from human dental stem cells." Bratislava Medical Journal-Bratislavske Lekarske Listy 120, no. 1 (2019): 86-88. 15. Hamidabadi, Hatef Ghasemi, Maryam Nazm Bojnordi, Nourollah Rezaei, and Sara Soleimani. "Evaluation of differential gene expression during transdifferentiation of bone marrow stromal cells to glial phenotype in the presence of cerebrospinal fluid." Avicenna journal of medical biotechnology 11, no. 1 (2019): 28. 16. Darabi, Shahram, Taki Tiraihi, Maryam Nazm Bojnordi, Hatef Ghasemi Hamidabadi, Nourollah Rezaei, Maria Zahiri, and Rafieh Alizadeh. "Trans-Differentiation of Human Dental Pulp Stem Cells Into Cholinergic-Like Neurons Via Nerve Growth Factor." Basic and Clinical Neuroscience 10, no. 6 (2019): 609. 17. Bojnordi, Maryam Nazm, Somayeh Ebrahimi‐Barough, Elham Vojoudi, and Hatef Ghasemi Hamidabadi. "Silk nanofibrous electrospun scaffold enhances differentiation of embryonic stem like cells derived from testis in to mature neuron." Journal of Biomedical Materials Research Part A 106, no. 10 (2018): 2662-2669. 18. Haratizadeh, Sara, Mohammad Ali Ebrahimzadeh, Maryam Nazm Bojnordi, Hatef Ghasemi Hamidabadi, Alireza Abdanipour, and Javad Akhtari. "Effect of Sambucus ebulus extract on neural stem cell prolifration under oxidative stress condition." Scientific Journal of Kurdistan University of Medical Sciences 23, no. 3 (2018): 26-35. 19. Ghasemi Hamidabadi, H., Rezvani, Z., Nazm Bojnordi, M., Shirinzadeh, H., Seifalian, A.M., Joghataei, M.T., Razaghpour, M., Alibakhshi, A., Yazdanpanah, A., Salimi, M., Mozafari, M., Urbanska, A.M., Reis, R.L., Kundu, S.C., Gholipourmalekabadi, M. Chitosan-Intercalated Montmorillonite/Poly(vinyl alcohol) Nanofibers as a Platform to Guide Neuronlike Differentiation of Human Dental Pulp Stem Cells. (2017) ACS Applied Materials and Interfaces, 9 (13), pp. 11392-11404. 20. 21. Bojnordi, Maryam Nazm, Hossein Azizi, Thomas Skutella, Mansoureh Movahedin, Fereshteh Pourabdolhossein, Amir Shojaei, and Hatef Ghasemi Hamidabadi. "Differentiation of spermatogonia stem cells into functional mature neurons characterized with differential gene expression." Molecular neurobiology 54, no. 7 (2017): 5676-5682. 22. Sara Haratizadeh1, Maryam Nazm Bojnordi1,2, Shahram Darabi3, Narges Karimi4, Mehrdad Naghikhani5, Hatef Ghasemi Hamidabadi1,6, Morteza Seifi. Condition medium of cerebrospinal fluid and retinoic acid induces the transdifferentiation of human dental pulp stem cells into neuroglia and neural like cells. Anat Cell Biol 2017;50:107-114. 23. Marzieh Sharifi Pasandi 1,2 & Farshad Hosseini Shirazi3,4 & Mohammad Reza Gholami5 & Hossein Salehi6 & Nowruz Najafzadeh7 & Mohammad Mazani2 & Hatef Ghasemi Hamidabadi8 & Ali Niapour7. Epi/perineural and Schwann Cells as Well as Perineural Sheath Integrity are Affected Following 2,4-D Exposure. Neurotox Res (2017) 32:624–638. 24. Hatef Ghasemi Hamidabadi, Maryam Nazm Bojnordi. Co-culture of mouse spermatogonial stem cells with sertoli cell as a feeder layer, stimulates the proliferation and spermatogonial stemness profile. Middle East Fertil Soc J (2017), http://dx.doi.org/10.1016/j.mefs.2017.09.004. 25. Moayeri, A., Nazm Bojnordi, M., Haratizadeh, S., Esmaeilnejad-Moghadam, A., Alizadeh, R., & Ghasemi Hamidabadi, H. (2017). Transdifferentiation of Human Dental Pulp Stem Cells Into Oligoprogenitor Cells. Basic and Clinical. Neuroscience, 8(5):387-394. 26. Ghasemi Hamidabadi H, Sobhani A, Nazm Bojnordi M. Multipotent SSEA-1 positive cells population differentiation into primordial germ cells and subsequently progress into oocyte-like cells. Arch Iran Med. 2015; 18(7): 404 – 410. 27. Nazm Bojnordi M1, Ghasemi HH1 and Akbari E Remyelination after Lysophosphatidylcholine -induced demyelination is stimulated using Bone Marrow Stromal Cell derived Oligoprogenitor cells transplantation. Cell Tissue Organ. 2015. 28. Sara Haratizadeh, Maryam Nazm Bojnordi, Ali Niapour, Mehrdad Bakhtiari, Hatef Ghasemi Hamidabadi. Improvement of Neuroglial Differentiation from Human Dental Pulp Stem Cells Using CSF.J Mazandaran Uni Med Sci 2016; 26 (140): 1-14 (Persian). 29. Ghazaleh Goudarzi1, Hatef Ghasemi Hamidabadi, Alireza Abdanipour, Homa Mohseni Kouchesfehani, Amir Esmaeilnejad Moghaddam. The Influence of Cerebrospinal Fluid Accompanied by Retinoic Acid on Differentiation of Bone Marrow Mesenchymal Stem Cells into Neuron-like Cells In Vitro. Pathobiology Research, Vol. 18 (2015-2016), No.4, Pages: 79-91. 30. Nazm Bojnordi M, Ghasemi Hamidabadi H.Spermatogonia stem cells: A new pluripotent source for repairment in regenerative medicine.RMM. 2015. 2015, Vol: 3, Issue: 1, Pages: 1- 4. 31. Gholipourmalekabadi M, Mozafari M, Gholipourmalekabadi M, Bojnordi MN, Hashemi-Soteh MB, Salimi M, Rezaei N, Sameni M, Samadikuchaksaraei A, Hamidabadi HG.In vitro and in vivo evaluations of three-dimensional hydroxyapatite/silk fibroin nanocomposites scaffolds. Biotechnol Appl Biochem. 2014 Sep 4 doi: 10.1002/bab.1285. 32. Nazm Bojnordi, M. Movahedin, T. Tiraihi M. Javan. H. Ghasemi Hamidabadi. Oligoprogenitor Cells Derived from Spermatogonia Stem Cells Improve Remyelination in Demyelination Model M. Mol Biotechnol DOI 10.1007/s12033-013-9722-0, Now 2013. 33. Gholipourmalekabadi M1, Mozafari M, Bandehpour M, Salehi M, Sameni M, Caicedo HH, Mehdipour A, Ghasemi H, Samadikuchaksaraei A, Ghanbarian H. Optimization of nanofibrous silk fibroin scaffolds as a delivery system for bone marrow adherent cells. Biotechnol Appl Biochem. 2014 Dec 4. doi: 10.1002/bab.1324. 34. Hatef Ghasemi Hamidabadi, Ph.D.1, Parichehr Pasbakhsh, Ph.D.1, Fardin Amidi, Ph.D.1, Masoud Soleimani, Ph.D.2, Mehdi Forouzandeh, Ph.D.3, Aligholi Sobhani, Ph.D. Functional Concentrations of BMP4 on Differentiation of Mouse Embryonic Stem Cells to Primordial Germ Cells. IJFS. Vol 5, No 2, Jul-Sep 2011, Pages: 104-109. 35. Hatef Ghasemi Hamidabadi, Nourollah Rezaei, Reza Mahmoudi, Maryam Nazm Bojnordi.Expression of Spermatogonial and Pluripotency markers in Spermatogonial stem cells after treatment with Different culture factors. Research in Molecular Medicine, 2014, Vol: 2, Issue: 2, Pages: 1-6. 36. Ghasemi Hamidabadi H, Ph.D., Rezaei N, Ph.D., Setorg R MSc, Abediankenari S, Ph.D., Latifpour M, Ph.D., Malekzadeh Shafarudi M The Concurrent Effect of 5-Azacytidin and DMSO on In Vitro Differentiation Induction of Cardiomyocytes from Embryonic Carcinoma cells P19. Journal of Cell & Tissue, Autumn 2014; 5(3): 317-324. Original Article. 37. Ebrahim Pour Malekshah R, M.Sc. 1, Malekzadeh Shafaroudi M, Ph.D.2, Ghasemi Hamidabadi H, Ph.D.2, Esmaeil Nejad Moghaddam A, Ph.D.2, Rezaei N, Ph.D.2* Investigating the Effect of Leptin on In Vitro Maturation, Fertilization and Embryonic Development of Immature Mouse Oocytes. Journal of Cell & Tissue (JCT) Original Article Winter 2015; 5(4): 409-416. 38. Nazm Bojnordi M,. Rezaei N, Ghasemi Hamidabadi H. Characterization of Pluripotency Markers Expression on ES-like Cells derive from Spermatogonia Stem Cells and Embryonic Stem Cells. Journal of Cell & Tissue (JCT) Original Article Summer 2014; 5(2): 147-155. 39. Majid Malekzadeh Shafaroudi., Nourolah Rezaei, Saeid Abedian kenari ., Raha Setorg, Mostafa Latifpour., Hatef Ghasemi Hamidabadi. The Effect of DMSO Inducer on In Vitro Differentiation of Cardiomyocytes from Embryonic Carcinoma cells P19. (2015) Illam university of medical science, 23 (1), 112-118. 40. Nikseresht M , Rasti T, Jafari Barmak M, Ghasemi Hamidabadi H, Rezaei Z, Dehghani F,Mahmoudi R. sjimu. In Vitro Maturation and Embryo Development to blastocyst Mouse Germinal Vesicle Oocytes after Vitrification. Armaghane-danesh, Yasuj University of Medical Sciences Journal (YUMSJ) November 7th 2016, 590-602. 41. Ghasemi H., M.Sc., Salehnia M., Ph.D., Batahi Z., Ph.D. Evaluation of Alkaline Phosphatase Activity Alteration in Mouse Endometrium after Ovarian. Hyperstimulation during Early Pseudo and Natural pregnancy until Implantation time. Journal of Iranian Sciences.2003 Autumn;3(3):173-184. 42. M.Nazm Bojnordi, M,Sc, M. Movahedin,Ph.D, S. Amanpour, Ph.D, H. Ghasemi Hamidabadi, M.Sc. Effect of Antioxidants supplemention on human sperm parameters after freezing. Journal of Mazandaran University of Medical Sciences.2008 May; 18(63):20-27. 43. H. Ghasemi Hamidabadi, M.Sc, Salehnia M., Ph.D, Batahi Z., Ph.D. A Camparitive Study of Mouse Ovarian Alkaline Phosphatase Activity in Normal and Psudopregnancies. Yakhteh Medical Journal.2006 spring; 8(1): 53-59. 44. Khoshvaghti A., Hatef Ghasemi, The Effect of Three-Dimensional Model on Anatomy Learning of Middle Ear. Journal of Iranian Anatomical Sciences, Vol 7, Autumn 2009 & Winter 2010, Pages 153-162. 45. Ghasemi HH, Sobhani A, Pasbakhsh P, Amidi F, Frozandeh A. In vitro Differentiation of Primordial Germ cells from Mouse Embryonic Stem Cells in Presences of Different Concentrations of Bone Morphogenic Protein 4. Journal of Cell and Tissue Research Vol. 11(2) 2741-2750 (2011). 46. Maedeh Entezari Najafabadi, AbbasaliKarimpour Malekshah, Amir Esmailnejad Moghaddam, Hatef Ghasemi Hamidabadi, Mahmoud Heidari.Effect of Embryonic Fibroblast Cells Conditioned Medium on in Vitro Maturation of Immature Mouse Oocytes. J Mazand Univ Med Sci 2014; 24 (Supple 1): 107-114 (Persian). 47. Malekzadeh Shafaroudi M, Rezaei N, Nazm Bojnordi M, Latifpour M, Ghasemi Hamidabadi H. An Efficient Protocol for Embryonic Carcinoma Cells P19 Differentiation to Cardiomyocytes Using Oxytocin as Inducer. Research in Molecular Medicine. 2016 Feb 15;4(1):24-9. 48. Rahgozar A, Hamidabadi HG, Shokri S, Moayeri A, Moghaddam AE. Effect of Human Chorionic Gonadotropin on the Destructive Effects of Nandrolone Decanoate on Sperm Parameters of Testes in Adult Rats. Armaghane Danesh Bimonthly Journal. 2015 Jan 1;20(9):811-24. 49. Kameli SM, Noori Mougehi, , Ghasemi Hamidabadi H. Effects of Gentamicin on Rabbit Newborn Spermatic Cords. Journal of Cell & Tissue (JCT). Winter 2014; 4(4): 407-414. 50. Navazesh A, Esmaeilnejad-Moghadam A, Karimpour-Malekshah AA, Rezaei N, Ghasemi H. The effect of freezing period on the viability and cleavage of two-cell embryos in mice. KAUMS Journal (FEYZ). 2014 Oct 15;18(5):405-10. 51. Behruzi M, Ghasemi Hamidabadi H, Gholipour Malekabadi M, Rezaei N, Nazm Bojnordi M, Malekzadeh Shafaroudi M. Using Hydroxyapatite-Gelatin Scaffold Seeded with Bone Marrow Stromal Cells as a Bone Graft in Animal Model. ISMJ. 2016 Nov 15;19(5):773-86. 52. Tadayoni S, Malekzadeh Shafarodi M, Ghasemi Hamidabadi H, Esmailnejad Moghaddam A, Khalilian A, Rezaei N. Effect of combination of Melatonin and All-Trans retinoic acid on maturation, fertilization and embryonic development of immature mouse oocytes. Journal of Gorgan University of Medical Sciences / 54Autumn 2015 / vol 17 / no 3. Review for journals: Journal of Mazandaran University of Medical Sciences, Mazandaran University of Medical Sciences, Sari, Iran. 2011- present. Cell journal (Yakhteh). 2015-present. Andrologia, 2016- present.

BIOGRAPHICAL SKETCH EZIO GIACOBINI, MD, PhD Ezio Giacobini, MD, PhD was from 1995 to 2020 a Professor associated with the Department of Internal Medicine, Rehabilitation and Geriatrics at the University of Geneva Faculty of Medicine and the University Hospital Geneva. His major research interests are both in the pre-clinical and clinical development of drug therapy for Alzheimer’s disease. Together with Robert Becker, he has developed, preclinically and clinically, two new cholinesterase inhibitors (Metrifonate and Pentastigmine) and participated in the clinical development of E20-20 (Donepezil), Rivastigmine and Phenserine. He is the author of over 300 peer-reviewed publications in international journals in the field of pharmacology, psychiatry and neurology. He also authored books, book chapters and articles in the field of neuropharmacology of the cholinergic system with a special interest in the area of Alzheimer’s disease therapy and cholinesterase inhibitors. He was the founder and organizer of the international meeting Advances in Alzheimer’s Therapy from 1988 to 2018. He received in July 2002, the Life Time Achievement Award in Alzheimer’s Disease Research from the Alzheimer Association (USA) at the 8th International Conference on Alzheimer’s Disease in Stockholm.

Alessandro Gialluisi holds a BSc in Biotechnologies (University of Bologna, 2007), and a MSc in Molecular Biology (University of Pisa, 2010). After spending a pre-doctoral research period at the Medical Genetics Unit of the Sant’Orsola-Malpighi hospital, University of Bologna (2010-2011), he started a PhD in the Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands, working on the genetics of reading and language abilities, and being awarded a PhD in Science (Radboud University Nijmegen, 2015). He continued investigating learning-related skills in his first post-doc (2015-2016) in the Statistical Genetics group, Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany. Then, he moved back to Italy to widen his spectrum of research interests to the molecular and genetic epidemiology of neurodegenerative and psychiatric disorders, at the Department of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Italy. He successfully completed a residency program in Medical Statistics and Biometry (Sapienza University of Rome, 2020), through a research project on the development and analysis of biological aging markers based on machine learning algorithms.

My name is Andreas Giannisis, and I am from Greece. Currently, I am a 3rd year Ph.D. student at the Department of Biochemistry and Biophysics, at Stockholm University, under the project: ‘‘Relevance of a peripheral apolipoprotein E linked phenotype to neurodegeneration’’, having Professor Henrietta Nielsen as my supervisor. I hold a bachelor’s degree in chemistry from the Department of Chemistry, at the University of Ioannina, Greece, and a master’s degree in Neurochemistry with Molecular Neurobiology from the Department of Biochemistry and Biophysics, at Stockholm University, Sweden.

Tiago André Braga Gião has completed his bachelor’s degree in Biochemistry at the Universidade do Minho in 2017. After he obtained his master’s degree in Applied Biochemistry with a specialization in Biomedicine in 2019, in the same institution. His master’s thesis was held in Porto at Instituto de Investigação e Inovação em Saúde (i3S). In the Molecular Neurobiology group, he dedicated himself to studying the role of Transthyretin (TTR) in brain vasculature in both physiological and pathological conditions (Alzheimer's Disease). Considering the known TTR neuroprotective effects, he also investigated TTR as a therapeutic target in Alzheimer's Disease. In 2020 he enrolled in the doctoral program in Molecular and Cellular Biology at the Universidade do Porto and continues to develop his work at i3S and he continue to study the role of TTR in the pathophysiology of AD.

Lucy Gibson is an Alzheimer's Society Clinical Research Fellow at King's College London.

Dr. Giliberto’s approach to Medicine, Neurology and Alzheimer’s disease (AD) has always been dual: basic research and clinical practice. He has worked and collaborated with great scientists, such as Massimo Tabaton, George Perry, Mark Smith, Pierluigi Gambetti, Antonio Uccelli, Luciano D’Adamio and Peter Davies. The work with Dr. D’Adamio at Albert Einstein College of Medicine, lead to identify APP processing modulators, including ITMB2 (BRI2). At the Feinstein Institutes, Dr. Giliberto collaborates with a diverse range of excellent scientists, expanding the focus of his research to tau, microglia and the immune response, cell cycle and the treatment of tau pathology with engineered antibodies. Dr. Giliberto works with patients affected by Alzheimer’s disease and other dementias, providing clinical care and trials, helping them and their families to cope with the disruption that this disease brings to their lives. This dual role has allowed him to broaden his view of the disease, as the inspiration he receives from patients at every encounter is invaluable. Dr. Giliberto teaches clinical neurology to medical students, Neurology, Medicine and Psychiatry residents at Hofstra University and North Shore University Hospital, and trains MD/PhD and PhD students in the laboratory at the Feinstein Institutes.

Dr. Gim is a principal investigator of gimLAB (genome intelligence mining laboratory) at the Department of Biomedical Science, Chosun University, Republic of Korea. He is also directing the Big-data Research Unit of the Gwangju Alzheimer's and Related Dementias (GARD) cohort, a community-based longitudinal cohort (n > 14,000). He is majored interdisciplinary field of science (theoretical particle physics, biostatistics and bioinformatics) and his research interests in AD studies are mostly focused on AD risk prediction and early diagnosis of AD using multi-modal dataset for the primary intervention purpose.

Helena Sophia Gleerup is a researcher at the Danish Dementia Research Centre, Rigshospitalet, Copenhagen University Hospital. She has a special interest in biomarkers, and her research has included investigating whether saliva can be a viable biofluid for the detection of biomarkers across different neurodegenerative disorders.