As a neuroscientist I am interested in the microscopic structure of the human brain, in particular how protein pathology relates to changes in the number of brain cells and cell-to-cell connections in neurodegenerative diseases. I study the brain at post-mortem, however, as the post mortem brains offers only a snapshot of the illness at the end stage, the ambition of my research is to assist in the development of new tools to map and track human brain illnesses. My current research explores such relationships in the severe and incurable neurodegenerative disorders, frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and multiple system atrophy (MSA).