Dr. Guy received his Ph.D. in Biophysics at the University of Illinois in 1974. Following a post-doc at the University of New York in Albany and serving as a Lieutenant in the Naval Medical Service Corp, he joined the National Institutes of Health in 1980. There he served as Chief of the Computational Structural Biology Section in the National Cancer Institute. He has published structural models of voltage-gated channels, mechanosensitive channels, VDAC, antimicrobial channels, potassium transporters, and amyloid beta and synuclein oligomers, protofibrils, and transmembrane channels. He served as North American Editor, Receptors & Channels from 1996-2000. His publications have been cited over six thousand times. He is currently CEO of ARC (Amyloid Research Consultants).