Alberto Benussi has acquired specialized skills in the field of neurodegenerative diseases, with particular interest in Alzheimer's disease, for sporadic and genetic forms of frontotemporal dementia, for atypical parkinsonisms and for rare diseases, such as Niemann-Pick type disease C and different forms of hereditary and sporadic ataxias. In this context he implemented and developed several neurophysiological protocols of transcranial magnetic stimulation (TMS), identifying some biomarkers of cortical connectivity both for the differential diagnosis of different neurodegenerative pathologies, and as preclinical disease biomarkers. The applications of these methods have been learned at Italian and foreign centres of excellence.