Dayanand Medical College and Hospital, Ludhiana
Department of Pediatrics
Dr Gurdeep Singh Dhooria (Professor of Pediatrics) is working as Consultant Pediatrics in the Department of Pediatrics since 2007. He is sincere and dedicated to his work and patient care. His main area of interest is Pediatric Infectious Diseases and Pediatric Nephrology and was instrumental in establishing Pediatric nephrology services in DMC. Dr Gurdeep was awarded visiting fellowship in Pediatric infectious diseases by Royal college of Pediatrics and Child Health (RCPCH), London UK. He has done Pediatric Nephrology fellowship from St Johns Medical College and Hospital, Ludhiana. He has many international and national publications including chapters in books and has presented papers in international and national conferences particularly related to Pediatric Nephrology and Pediatric Infectious diseases. He is a master trainer of "Asthma training" and "Tuberculosis" modules of IAP. Dr Gurdeep is also PALS instructor and holds BLS and other workshops for medicos in Punjab. He is also life member of different international societies.

Presenter Of 2 Presentations

COMPARISON OF CLINICAL FEATURES AND OUTCOME OF DENGUE FEVER AND MIS-C IN CHILDREN

Session Type
Workshop
Date
Sun, 20.02.2022
Session Time
10:00 AM - 01:00 PM
Room
Sala A
Session Icon
Pre-Recorded with Live Q&A
Lecture Time
10:50 AM - 11:02 AM

COMPARISON OF CLINICAL FEATURES AND OUTCOME OF DENGUE FEVER AND MIS-C IN CHILDREN

Session Type
Oral Presentations
Date
Wed, 23.02.2022
Session Time
11:15 AM - 12:15 PM
Room
Sala E
Session Icon
Pre-Recorded with Live Q&A
Lecture Time
11:25 AM - 11:35 AM

Abstract

Background

MIS-C is an inflammatory condition following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Aims

To identify clinical and laboratory features that differentiate dengue fever patients from MIS-C patients and determine their outcomes

Methods

This comparative cross-sectional study was
done at tertiary care teaching institute. We enrolled all hospitalized children aged 1 month - 18 years and diagnosed with either MIS-C and/or dengue fever according to WHO criteria between June and December, 2020. Clinical and laboratory features and outcomes were recorded on a structured proforma.

Results

During study 34 cases of MIS-C and 83 cases of Dengue fever were
enrolled. Mean age of MIS-C cases (male, 86.3%) was 7.89 (4.61) years. Of 34 cases, MIS-C with shock was seen in 15 (44%), MIS-C without shock, 17 (50%) and Kawasaki disease-like presentation in 2 cases (6%). Patients of MIS-C were younger as compared to dengue fever (P=0.002). Conjunctival injection and swelling of hand and feet were more commonly seen in MIS-C.
Abdominal pain and erythematous rash were more common in dengue fever. Of the inflammatory markers, mean C reactive protein was higher in MIS-C patients, than dengue fever patients [100.2 (85.1) vs 16.9 (29.3) mg/dL (P<0.001). In contrast, serum ferritin levels were higher in dengue fever patients (P=0.03). Need for mechanical ventilation was significantly more in MIS-C cases. Mean
hospital stay was longer in MIS- C patients days compared to dengue fever (8.6 vs 6.5 days; P=0.014)

Conclusions

Clinical and laboratory features can give important clues to differentiate dengue fever and MIS-C and help initiate specific treatment.

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