Seoul St. Mary's Hospital
Department of pediatrics
Ye Ji Kim, M.D. Department of Pediatrics, Seoul St. Mary's Hospital 222, Banpo-daero, Seocho-gu, Seoul, Republic of Korea, 06591

Presenter Of 1 Presentation

SOURCE IDENTIFICATION AND INTERVENTION MEASURES TAKEN TO SUCCESSFULLY CONTROL TWO NOSOCOMIAL INFECTION OUTBREAKS AT A NEONATAL INTENSIVE CARE UNIT

Session Type
Oral Presentations
Date
Wed, 23.02.2022
Session Time
11:15 AM - 12:25 PM
Room
Sala A
Session Icon
Pre-Recorded with Live Q&A
Lecture Time
11:15 AM - 11:25 AM

Abstract

Background

Neonates in the neonatal intensive care units(NICUs) are vulnerable to nosocomial infections, which in turn are associated with increased infection-related morbidities and mortalities.

Aims

This study aimed to identify the sources of Enterococcus faecium/Staphylococcus capitis outbreak and describe effective infection control measures applied to terminate two nosocomial infection outbreaks.

Methods

Two outbreaks occurred during an 85-day period in two disconnected subunits, that share the same attending physicians. A total of 7 cases of sepsis occurred. Environmental surveillances including Adenosine triphosphate(ATP) bioluminescence assay monitoring and environmental cultures were carried out in parallel to 29 healthcare workers’ hand cultures.

Results

During 4 years prior to the outbreaks, a total of 260 neonatal sepsis occurred. CoNS(n=164,63%), VSE(n=32,12.3%), MRSA(n=21,8.1%), were reported as the most common pathogens. Coincidentally, the causative pathogens of the outbreaks were E. faecium(n=4/7) and S. capitis(n=3/7). In the environmental cultures, both were cultured from both medical and non-medical devices located remotely from the patients. ATP titers were found to be the highest on a keyboard(2706 RLU). Hand cultures were done, and S. capitis was cultured in n=9/29(31%). All S. capitis obtained from the environments as well as hands that had similar antibiotic sensitivity profiles with the pathogen underwent Pulsed-Field Gel Electrophoresis, showing identical genotypes. The following interventions were applied:changing keyboards to sanitizable medical ones, changing methods and frequencies of universal and targeted environmental disinfection. No more infections by the nosocomial pathogens of the outbreak have occurred since, then.

Conclusions

We identified that the colonized pathogens on non-medical devices can be a source of infection.

Hide