My research is focused on the "GUT-BRAIN Axis” in aging. We are investigating how the interaction of the microbiome and their secretory products affect the gut physiology and thereby modulate physiology of brain in diseases outcomes specifically stroke, AD and Cerebral amyloid angiopathy (CAA). The long-term goal of my research is to elucidate the role of intestinal microbiome in interfering with intestinal epithelial homeostasis causing onset and activation of chronic inflammation with respect to neurological diseases including dementia. We hope to use commensal bacteria to beneficially modify the peripheral immune response in a hope to reduce the neuroinflammation after injury of the brain. This we term as "microbial therapy" that targets mainly in reducing immune response of the gut and brain via systemic and vagal stimulation.

Dr. Gauberti is interventional neuroradiologist in the department of radiology at Caen University Hospital. He is deputy director of a research team focused on thrombolysis and neurovascular disorders. He is currently working on new thrombolytic strategies for stroke (including N-Acetylcysteine) and new contrast agents for Magnetic Resonance Imaging (immuno-MRI).

Dr. Gottesman is currently Stroke Branch Chief and Senior Investigator of the Stroke, Cognition, And Neuroepidemiology (SCAN) section at the NINDS Intramural program. Before coming to the NINDS in 2021, she was Professor of Neurology and Epidemiology at the Johns Hopkins University School of Medicine, where she maintains an adjunct faculty appointment. Dr. Gottesman completed her undergraduate and medical training at Columbia University, and her internship and neurology residency, as well as Vascular neurology fellowship at Johns Hopkins. She completed a PhD in Clinical Investigation at the Hopkins Bloomberg School of Public Health, and her research focuses on the vascular contributions to cognitive impairment, dementia, and Alzheimer’s disease, as well as on cerebral small vessel disease and post-stroke dementia. She primarily studies large epidemiologic cohorts and uses neuroimaging to evaluate mechanism related to these research questions. She also studies disparities in stroke, dementia, and post-stroke cognitive impairment. She is a former Associate Editor for the journal Neurology, won the 2019 Outstanding Stroke Research Mentor award from the American Heart Association (AHA).

Dr Grimley is an experienced clinician researcher and an established leader in translation of evidence into practice across health systems. He works as an acute stroke physician (geriatrician) at the Sunshine Coast University Hospital, Queensland Australia, and is Associate Professor in the School of Medicine, Griffith University. He has led systematic change in stroke care across Queensland through development of stroke units, use of data to support improvement in quality of care, and access to rehabilitation.

Dr. James Grotta received his education at Dartmouth College, the Universities of Virginia and Colorado, and Massachusetts General Hospital. After joining the UT Houston faculty in 1979, he established the UT Houston Stroke Program and developed its NIH funded fellowship training program. He has been continuously funded to carry out translational research in acute stroke treatment, and played a leading role in many clinical research studies, including the NINDS TPA Stroke Study. In 2013, Dr. Grotta stepped down as department chair and moved his practice to Memorial Hermann Hospital to lead the Mobile Stroke Unit Consortium, the nation's first Mobile Stroke Unit to deliver TPA and other stroke therapies wherever the stroke occurs. In 2021 he completed a prospective multicenter comparative effectiveness study of this novel approach to acute stroke treatment. He edits the most authoritative textbook on Stroke, has published over 500 scientific manuscripts, and has received numerous awards for his research, clinical work and mentoring.