Abstract Body

The two goals of the diagnostic workup in transient ischemic attack (TIA) are first, to demonstrate that the experienced symptoms were actually caused by a TIA and second, to identify the etiology of the TIA to start personnalized secondary prevention. Recent progress in imaging and bioengineering could change the way we approach the diagnosis of TIA. For instance, preclinical studies demonstrated that we can detect cerebral endothelial activation resulting from a TIA by molecular MRI, even in the absence of cerebral infarction. Other approaches aiming at detecting atherosclerotic plaque rupture or left atrial appendage thrombosis are also under investigation. The most recent developments in preclinical and clinical diagnostic tools will be presented.