Western University
Clinical Neurological Sciences
Dr. Luciano Sposato is a Professor of Neurology at the Department of Clinical Neurological Sciences, London Health Sciences Centre (LHSC), Western University, London, ON, Canada. He is a stroke neurologist and clinician-researcher, with cross appointments with the Departments of Epidemiology & Biostatistics and Anatomy and Cell Biology (Western University). Dr. Sposato is the Head of the Stroke Program, he holds the Barnett Chair in Stroke Research, and is the Director of the Heart & Brain Lab, at Western University. He is the Chair of the World Stroke Organisation Brain & Heart Task Force, and Associate Scientist at Robarts Research Institute. He is member of the Editorial Board and serves as Editor of the Neurocardiology Section of STROKE (American Heart Association), is member of the Editorial Board of NEUROLOGY (American Academy of Neurology) and JAHA, and serves as Associate Guest Editor for JAHA. Dr. Sposato’s research focuses on the Brain & Heart connection and leads a multidisciplinary and translational research program involving epidemiological, clinical, and experimental studies. Among his most impactful contributions, he described the clinical and pathophysiological concept of AFDAS (atrial fibrillation detected after stroke) and the pathophysiological process leading to cardiovascular complications in stroke patients, called SIHI (stroke-induced heart injury). He has published over 150 papers in the field.

Presenter of 1 Presentation

PFOs: To Close or Not to Close

Session Type
Satellite Session
Date
28.10.2021, Thursday
Session Time
15:45 - 17:15
Room
WSC TV
Lecture Time
16:36 - 16:53

Abstract

Abstract Body

Patent foramen ovale (PFO) is a prevalent cause of ischemic stroke and transient ischemic attack (TIA) in young adults. Randomized controlled trials (RCTs) have shown that PFO closure is associated with a 59% relative risk reduction in the risk of recurrent ischemic stroke. As such, the number of PFO closure procedures is expected to increase. There are certain stroke patients who may benefit from PFO closure that were not sufficiently represented in clinical trials. Dr. Sposato will address uncertainties in the management of patients with ischemic stroke and TIA beyond data from randomized clinical trials

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