Yvo Roos is professor of acute neurology, vice-head of the department of neurology and vice-chairman of the head and neck division in the Amsterdam University Medical Center. He was founder of the Acute Brain Care Unit (ABC-Unit) in 1996 which served as a blueprint for acute stroke care management, including CT-scanning and thrombolysis, in the Netherlands. He was Co-PI of the MRCLEAN trial; Co-PI of the MRCLEAN Registry; PI of the MRCLEAN No-IV within the CONTRAST consortium; executive committee member of HERMES, pooling 7 RCT’s on endovascular treatment of acute ischemic stroke; Co-PI of DIRECT MT trial. He is Chairman of StrokeNet (regional stroke care optimization) and Research leader of the Dutch Heart Foundation-funded ‘Circulating Nano Traces to Identify the Cause of Stroke’ (CINTICS), a research collaboration of the University of Amsterdam, Delft University of Technology, the University of Leiden and the Erasmus University Rotterdam. With the MRCLEAN co-PI’s he has won several prestigious prizes and awards – i.e. the Science and Innovation Award from the Dutch Federation of Medical Specialists and the Excellence and Innovation Award CIRSE (2017). In 2020 they won the Winkler Medal of the Dutch Neurology Society. He has (co-)authored over 350 papers (H-index of 56).