Ludo Beenen (Netherlands)
Amsterdam UMC RadiologyAuthor Of 1 Presentation
ASSOCIATION BETWEEN THROMBUS CHARACTERISTICS, SUCCESSFUL REPERFUSION AND FUNCTIONAL OUTCOME AFTER ENDOVASCULAR TREATMENT IN PATIENTS WITH POSTERIOR CIRCULATION STROKE.
Abstract
Background and Aims
Thrombus perviousness and length are important thrombus imaging characteristics related to outcome in patients with anterior circulation ischemic stroke. We investigated the association of thrombus characteristics with reperfusion and functional outcome in patients with posterior circulation stroke (PCS) who underwent endovascular treatment (EVT).
Methods
Thrombus imaging characteristics (perviousness, density, and length) were measured in patients with PCS registered in the MR CLEAN Registry between 2014-2018. All characteristics were assessed on thin-slice (<2.5mm) non-contrast computed tomography and computed tomography angiography imaging acquired within 30 minutes from each other. We compared thrombus characteristics in patients with or without excellent reperfusion (expanded Treatment In Cerebral Ischemia (eTICI) score ≥2C) and with or without favorable functional outcome (modified Rankin Scale score (mRS) 0-3) using the Mann-Whitney U-test.
Results
Sixty-six patients were analyzed. Median thrombus perviousness was 7 (IQR -1-21) Hounsfield Units (HU). Median density was 54 (IQR 44-66) HU and median length was 24 (IQR 15-42) mm. No significant between-group differences were found in thrombus characteristics (Table 1).
| eTICI<2C (n=32) | eTICI≥2C (n=29) | p value | mRS 0-3 (n=27) | mRS 4-6 (n=37) | p value | |
| Thrombus imaging characteristics | ||||||
| Length (mm), median (IQR) | 24 (14-49) | 21 (15-29) | 0.45 | 21 (15-29) | 25 (15-48) | 0.24 |
| Perviousness (HU), median (IQR) | 11 (1-21) | 7 (-4-18) | 0.42 | 2 (-2-20) | 10 (1-21) | 0.29 |
| Density (HU), median (IQR) | 55 (47-66) | 51 (43-62) | 0.63 | 55 (43-66) | 50 (44-65) | 0.64 |
Conclusions
In this study of patients with PCS treated with EVT, thrombus imaging characteristics were not associated with reperfusion or functional outcome.