Nataliya Marskaya (Russian Federation)
Federal State Budgetary Institution «Federal center of brain research and neurotechnologies» of the Federal Medical Biological Agency Institute of Cerebrovascular Pathology and StrokeAuthor Of 1 Presentation
SUBTYPES OF ACUTE ISHEMIC STROKE IN YOUNG ADULTS: DATA FROM THE MOSCOW HOSPITAL STROKE REGISTRY
Abstract
Background and Aims
Determining the subtypes and the mechanism of the development of acute ischemic stroke (AIS) is important for choosing the tactics of secondary prevention of stroke in young adults. A research aim was to study the structure of AIS in a group of young adults under 45 years old based on data from the Moscow Hospital Stroke Register (MHSR).
Methods
The MHSR has been held since 2017, it includes all patients with acute cerebrovascular diseases hospitalised in stroke units. This retrospective analysis included data from patients aged 18 to 45 years of the MHSR from 28 stroke units in Moscow for the period from 2017 to 2019. Based on clinical, instrumental and laboratory data, subtypes of AIS were determined according to the TOAST criteria.
Results
A total of 85514 cases of AIS were registered with the proportion of young strokes was 3.8% (3243 cases). After excluding incomplete data, 2878 cases (male 62,3%, median age 38,6) were included in the final analysis. The most frequent subtype of AIS was stroke of undetermined etiology (1398 cases, 48,6%), followed by large-artery atherosclerosis (681 cases, 23,7%), small-vessel occlusion (512 cases, 17,8%), cardioembolism (223 cases, 7,7%). Stroke of other determined etiology accounted for 64 cases, 2,2% (Picture).
Conclusions
In the first large-scale Russian registry study of AIS, we researched the representation of different subtypes of AIS in young adults, to be used in choosing the strategy of secondary stroke prevention.