Welcome to the WCN 2021 Interactive Program
The congress will officially run on Central European Time (CET) - Rome Time
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Please note that all sessions will run at their scheduled time and be followed by a LIVE Q&A/Discussion at the end
The viewing of sessions, cannot be accessed from this conference calendar. All sessions are accessible via the Virtual Platform
- Pietro Cortelli (Italy)
AUTONOMIC PERIPHERAL NEUROPATHY
- Roy Freeman (United States of America)
SLEEP DISORDERS AND THE AUTONOMIC NERVOUS SYSTEM
- Federica Provini (Italy)
Abstract
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SLEEP DISORDERS AND AUTONOMIC NERVOUS SYSTEM
Federica Provini
IRCCS, Istituto delle Scienze Neurologiche di Bologna
Department of Biomedical and Neuromotor Sciences, University of Bologna Italy
Sleep and autonomic nervous system (ANS) are interdependent by virtue of their common controls, neurobiological substrates and functions. Major confirmation of this is the presence of dynamic and synchronous fluctuations in sleep phases and autonomic variables during the physiological sleep.
Much evidence from experimental and clinical studies supports the bidirectional nature of the relationship between sleep disorders and ANS dysfunctions. Patients with autonomic dysfunctions may present sleep disorders and conversely patients with untreated sleep disorders may develop features suggestive of autonomic dysfunctions.
In many neurodegenerative disorders sleep-wake cycle disorders appear in almost all or in all patients, often associated with autonomic dysfunctions, with a negative prognostic impact, particularly when involving cardiovascular or respiratory control.
In neurodegenerative diseases, the pathological disruption of sleep microstructure leads to an insufficient response to potential internal or environmental disruptors. In these conditions the sleeping brain offers a fragile interface against ongoing menaces as the paucity of EEG arousals responses mirrors the shortage of autonomic reactions.
In all these conditions, an accurate analysis of sleep disorders and autonomic dysfunctions is of crucial importance to choose the proper therapeutic approach.
THERAPEUTIC OPTIONS IN AUTONOMIC DISORDERS
- Alessandra Fanciulli (Austria)
Abstract
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An individualized management of autonomic disorders requires a careful preliminary assessment not only of the type and severity degree of autonomic failure, but also of the patient’s preferences, therapeutic expectations and other disease-related aspects, such as the presence of motor or cognitive impairment. Non-pharmacological and pharmacological options are to be introduced in a stepwise fashion based on the symptomatic burden in single patients. Any interventional measure also requires a close follow-up to monitor for the therapeutic outcome, compliance and eventual side effects.