Etienne C. Hirsch (France)

Paris Brain Institute, INSERM, CNRS and Sorbonne University Exeprimental therapeutics of Parkinson disease
Etienne Hirsch is a neurobiologist involved in research on Parkinson’s disease and related disorders. He obtained his PhD in 1988 from the University of Paris VI (Pierre et Marie Curie). He is currently the director of the National Insitute for Neurosciences, Cognitive sciences, Neurology and Psychiatry at INSERM (French NIH) and the French alliance for life and health science Aviesan, head of “Experimental therapeutics of Parkinson disease” at the ICM at Pitié-Salpêtrière hospital in Paris and since November 2015 in charge of the research aspects of French national plan on neurodegenerative disorders . His work is aimed at understanding the cause of neuronal degeneration in Parkinson’s disease and is focused on the role of the glial cells, the inflammatory cytokines and apoptosis but also on the consequences of neuronal degeneration in the circuitries downstream to the lesions. He obtained several prizes including Tourette Syndrome Association Award in1986, Young researcher Award, European Society for Neurochemistry in 1990, Grand Prix de l’Académie de Sciences, Prix de la Fondation pour la recherche biomédicale « Prix François Lhermitte » in 1999, Chevalier de l’ordre des palmes académiques in 2009, Prix Raymond et Aimée Mande of the French National academy of Medicine in 2011, elected Member of the French National Academy of Pharmacy in 2011. He is author of more than 350 peer reviewed articles.

Author Of 1 Presentation

Scientific Session: T (Topics)

PARKINSON DISEASE: A TARGET FOR THERAPIES?

Session Type
Scientific Session: T (Topics)
Date
05.10.2021, Tuesday
Session Time
17:10 - 18:40
Room
Topic D
Lecture Time
17:56 - 18:19
Presenter
  • Etienne C. Hirsch (France)

Abstract

Abstract Body

Parkinson's disease is a progressive and debilitating disorder that has so far eluded attempts to develop disease-modifying treatment. Both epidemiological and genetic studies support a role of neuroinflammation in the pathophysiology of Parkinson's disease. Postmortem studies and experimental analyses suggest the involvement of both innate and adaptive immunity in the degenerative process. There is also some circumstantial evidence for effects of immune therapies on the disease. In this presentation, I will review 10 unanswered questions related to neuroinflammatory processes in Parkinson's disease with the goal of stimulating research in the field and accelerating the clinical development of neuroprotective therapies based on anti-inflammatory strategies.

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Presenter of 1 Presentation

Scientific Session: T (Topics)

PARKINSON DISEASE: A TARGET FOR THERAPIES?

Session Type
Scientific Session: T (Topics)
Date
05.10.2021, Tuesday
Session Time
17:10 - 18:40
Room
Topic D
Lecture Time
17:56 - 18:19
Presenter
  • Etienne C. Hirsch (France)

Abstract

Abstract Body

Parkinson's disease is a progressive and debilitating disorder that has so far eluded attempts to develop disease-modifying treatment. Both epidemiological and genetic studies support a role of neuroinflammation in the pathophysiology of Parkinson's disease. Postmortem studies and experimental analyses suggest the involvement of both innate and adaptive immunity in the degenerative process. There is also some circumstantial evidence for effects of immune therapies on the disease. In this presentation, I will review 10 unanswered questions related to neuroinflammatory processes in Parkinson's disease with the goal of stimulating research in the field and accelerating the clinical development of neuroprotective therapies based on anti-inflammatory strategies.

Hide