Etienne C. Hirsch (France)
Paris Brain Institute, INSERM, CNRS and Sorbonne University Exeprimental therapeutics of Parkinson diseaseAuthor Of 1 Presentation
PARKINSON DISEASE: A TARGET FOR THERAPIES?
- Etienne C. Hirsch (France)
Abstract
Abstract Body
Parkinson's disease is a progressive and debilitating disorder that has so far eluded attempts to develop disease-modifying treatment. Both epidemiological and genetic studies support a role of neuroinflammation in the pathophysiology of Parkinson's disease. Postmortem studies and experimental analyses suggest the involvement of both innate and adaptive immunity in the degenerative process. There is also some circumstantial evidence for effects of immune therapies on the disease. In this presentation, I will review 10 unanswered questions related to neuroinflammatory processes in Parkinson's disease with the goal of stimulating research in the field and accelerating the clinical development of neuroprotective therapies based on anti-inflammatory strategies.
Presenter of 1 Presentation
PARKINSON DISEASE: A TARGET FOR THERAPIES?
- Etienne C. Hirsch (France)
Abstract
Abstract Body
Parkinson's disease is a progressive and debilitating disorder that has so far eluded attempts to develop disease-modifying treatment. Both epidemiological and genetic studies support a role of neuroinflammation in the pathophysiology of Parkinson's disease. Postmortem studies and experimental analyses suggest the involvement of both innate and adaptive immunity in the degenerative process. There is also some circumstantial evidence for effects of immune therapies on the disease. In this presentation, I will review 10 unanswered questions related to neuroinflammatory processes in Parkinson's disease with the goal of stimulating research in the field and accelerating the clinical development of neuroprotective therapies based on anti-inflammatory strategies.