Mohammad Wasay (Pakistan)
Aga Khan University NeurologyAuthor Of 2 Presentations
ADVOCACY; IDEA, EXECUTION AND MAKING A DIFFERENCE
- Mohammad Wasay (Pakistan)
ENVIRONMENT, STROKE AND DEMENTIA
- Mohammad Wasay (Pakistan)
Abstract
Abstract Body
Air pollution, stroke and dementia
Mohammad wasay MD FRCP FAAN
Recent studies have shown air pollution and PM to be associated with neuroinflammation and reactive oxygen species (ROS). High concentration of O3 in the environment is associated with a 211% increase risk of AD onset. A recent study showed that people living in a polluted environment having high concentrations of O3 had a 34% faster rate of cognitive decline annually on the Mini Mental Status Examination (MMSE) as compared to those exposed to lower concentrations of O3 . PM exposure is also reported to cause 138% increase in risk of AD onset. Oudin et al. reported that residents exposed to high traffic-related pollution had greater than 40% increase in incidence of AD or vascular dementia. The Global Burden of Disease Study 2013 found 29.2% of the global stroke burden to be attributable to air pollution. Furthermore, a meta-analysis of 94 studies found stroke hospital admissions to be associated with high concentrations of carbon monoxide, sulfur dioxide and nitrogen dioxide. The “European Study of Cohorts for Air Pollution Effects” project reported that even a small increase of about 5 ml/m3 in PM2.5 concentration in the air was associated with 19% increase risk of stroke. There is need for additional robust observational and experimental studies highlighting harmful air pollutants and their association with common neurological disorders. Safety measures and effective strategies to curb air pollution need to be implemented alongside increase in public awareness.
Presenter of 2 Presentations
ADVOCACY; IDEA, EXECUTION AND MAKING A DIFFERENCE
- Mohammad Wasay (Pakistan)
ENVIRONMENT, STROKE AND DEMENTIA
- Mohammad Wasay (Pakistan)
Abstract
Abstract Body
Air pollution, stroke and dementia
Mohammad wasay MD FRCP FAAN
Recent studies have shown air pollution and PM to be associated with neuroinflammation and reactive oxygen species (ROS). High concentration of O3 in the environment is associated with a 211% increase risk of AD onset. A recent study showed that people living in a polluted environment having high concentrations of O3 had a 34% faster rate of cognitive decline annually on the Mini Mental Status Examination (MMSE) as compared to those exposed to lower concentrations of O3 . PM exposure is also reported to cause 138% increase in risk of AD onset. Oudin et al. reported that residents exposed to high traffic-related pollution had greater than 40% increase in incidence of AD or vascular dementia. The Global Burden of Disease Study 2013 found 29.2% of the global stroke burden to be attributable to air pollution. Furthermore, a meta-analysis of 94 studies found stroke hospital admissions to be associated with high concentrations of carbon monoxide, sulfur dioxide and nitrogen dioxide. The “European Study of Cohorts for Air Pollution Effects” project reported that even a small increase of about 5 ml/m3 in PM2.5 concentration in the air was associated with 19% increase risk of stroke. There is need for additional robust observational and experimental studies highlighting harmful air pollutants and their association with common neurological disorders. Safety measures and effective strategies to curb air pollution need to be implemented alongside increase in public awareness.
Moderator of 2 Sessions
- Wolfgang Grisold (Austria)
- Mohammad Wasay (Pakistan)
- Mohammad Wasay (Pakistan)