Welcome to SIOP 2022 Interactive Programme

The Congress will officially run on CET time zone (Central European Time, Barcelona)

Displaying One Session

1910 - SATELLITE SYMPOSIUM 04 (not included in main event CME/CPD credit)

Session Type
SATELLITE SYMPOSIUM
Date
10/01/2022
Session Time
12:25 PM - 01:25 PM
Room
Room 112
Session Description
Reducing cisplatin-induced hearing loss: The current scene & future directions - Symposium Supported by Fennec Pharmaceutical Description: Cisplatin-based therapy is often an indispensable component of treatment for several common pediatric cancers, but is widely associated with irreversible, bilateral, progressive hearing loss. This hearing loss can have a profound, multifaceted impact on children which persists and evolves over the child’s lifetime. Two randomized clinical trials have demonstrated that Pedmark (novel formulation of STS, Sodium Thiosulfate) reduces the risk of hearing loss in pediatric patients receiving cisplatin. Pedmark is being developed as a therapeutic agent to prevent Cisplatin Induced Ototoxicity (CIO) and is under regulatory review.In this session, Dr. Penelope Brock will set the scene for two novel Phase 2 clinical trials where Pedmark will be administered to pediatric patients with different diseases aiming to prevent CIO. In the first presentation Dr. James Geller will describe a clinical trial to investigate the effect of Pedmark in relapsed/refractory hepatoblastoma and other embryonal tumors. In the second presentation, Dr. Eiso Hiyama will present a clinical trial where Pedmark will be administered and pharmacokinetically monitored in pediatric patients aged 3 -18 years with newly diagnosed solid tumors. The session will be followed by a panel and audience discussion.

REDUCING CISPLATIN-INDUCED HEARING LOSS: THE CURRENT SCENE & FUTURE DIRECTIONS - SYMPOSIUM SUPPORTED BY FENNEC PHARMACEUTICAL

Session Type
SATELLITE SYMPOSIUM
Date
10/01/2022
Session Time
12:25 PM - 01:25 PM
Room
Room 112
Lecture Time
12:25 PM - 12:25 PM

CISPLATIN INDUCED HEARING LOSS: INFORMING, MONITORING AND UPFRONT PREVENTION

Session Type
SATELLITE SYMPOSIUM
Date
10/01/2022
Session Time
12:25 PM - 01:25 PM
Room
Room 112
Presenter
  • Penelope R. Brock (United Kingdom)
Lecture Time
12:25 PM - 12:40 PM

SODIUM THIOSULFATE (ANHYDROUS) OTOPROTECTION DURING SALVAGE CISPLATIN THERAPY

Session Type
SATELLITE SYMPOSIUM
Date
10/01/2022
Session Time
12:25 PM - 01:25 PM
Room
Room 112
Presenter
  • James Geller (United States of America)
Lecture Time
12:40 PM - 01:00 PM

PHASE II (STS-J01) STUDY OF SODIUM THIOSULFATE ANHYDROUS TO REDUCE THE RISK OF CISPLATIN-INDUCED OTOTOXICITY IN JAPANESE PEDIATRIC AND AYA PATIENTS WITH MALIGNANCIES

Session Type
SATELLITE SYMPOSIUM
Date
10/01/2022
Session Time
12:25 PM - 01:25 PM
Room
Room 112
Presenter
  • Eiso Hiyama (Japan)
Lecture Time
01:00 PM - 01:25 PM