Author Of 1 Presentation
P0292 - Associations between treatment satisfaction, medication beliefs, and adherence to DMT in MS patients: Saudi Tertiary Care Center Experience (ID 112)
Abstract
Background
Multiple sclerosis (MS) considered as one of the most common Neuro-immune diseases that leads to major disabilities in an affected patient with a significant burden and consequences to patients and their families. Even though till these days there is no available cure for MS, however, the last two decades witnessed a promising future for MS treatments drugs precisely disease-modifying therapies (DMTs) to reduce MS relapse and delay disability.
Adherence to DMTs has a significant impact on treatment outcomes and is considered a critical factor in succeeding therapeutic success. Accordingly, the need to examine this issue in Saudi Arabia stands.
Objectives
To identify the factors associated with adherence to DMTs medications among MS patients in Saudi Arabia.
To evaluate the relationship between treatment satisfaction, medication beliefs, and DMTs adherence, and other factors
Methods
A survey was conducted in 2019 in neurology clinics in King Fahad Medical City (KFMC) in Riyadh. Patients were sampled from the KFMC’s Data Base with population size of 387 patients. The survey measured self-reported DMT adherence (doses taken divided by doses prescribed during previous 2-week period—adherence ≥0.80), DMT satisfaction using the Treatment Satisfaction Questionnaire for Medication version II, medication beliefs using the Beliefs About Medicines Questionnaire, and demographic and clinical covariates. Relationships between variables were examined using multivariate logistic regression.
Results
Final analyses included 239 usable surveys. Mean ± SD participant age was 35.07 ± 9.7 years. Most respondents were female (74.9%)), taking an injectable DMT (49%), and adherent to DMT (64.4%). Significant predictors of DMT adherence were DMT Experience (naive vs. experienced (odds ratio [OR], 3.722; 95% CI, 1.487 - 9.316; P = .005), DMT Rout (oral vs. injectable; OR, 0.974; 95% CI, 0.952 - 0.995; P = .017), and Global Satisfaction; OR, 0.950; 95% CI, 0.926 - 0.975; P = <0.001)
Conclusions
In patients with MS sampled from KFMC’s Data Base, medication beliefs was not significantly associated with DMT adherence while the Global satisfaction was significantly associated with DMT adherence. Based on significant predictors, patients taking injectable DMTs, and patients with previous experience with another DMT(s) are at higher risk for no adherence. Future research is warranted to assess relationships between variables in more diverse MS populations.
Presenter Of 1 Presentation
P0292 - Associations between treatment satisfaction, medication beliefs, and adherence to DMT in MS patients: Saudi Tertiary Care Center Experience (ID 112)
Abstract
Background
Multiple sclerosis (MS) considered as one of the most common Neuro-immune diseases that leads to major disabilities in an affected patient with a significant burden and consequences to patients and their families. Even though till these days there is no available cure for MS, however, the last two decades witnessed a promising future for MS treatments drugs precisely disease-modifying therapies (DMTs) to reduce MS relapse and delay disability.
Adherence to DMTs has a significant impact on treatment outcomes and is considered a critical factor in succeeding therapeutic success. Accordingly, the need to examine this issue in Saudi Arabia stands.
Objectives
To identify the factors associated with adherence to DMTs medications among MS patients in Saudi Arabia.
To evaluate the relationship between treatment satisfaction, medication beliefs, and DMTs adherence, and other factors
Methods
A survey was conducted in 2019 in neurology clinics in King Fahad Medical City (KFMC) in Riyadh. Patients were sampled from the KFMC’s Data Base with population size of 387 patients. The survey measured self-reported DMT adherence (doses taken divided by doses prescribed during previous 2-week period—adherence ≥0.80), DMT satisfaction using the Treatment Satisfaction Questionnaire for Medication version II, medication beliefs using the Beliefs About Medicines Questionnaire, and demographic and clinical covariates. Relationships between variables were examined using multivariate logistic regression.
Results
Final analyses included 239 usable surveys. Mean ± SD participant age was 35.07 ± 9.7 years. Most respondents were female (74.9%)), taking an injectable DMT (49%), and adherent to DMT (64.4%). Significant predictors of DMT adherence were DMT Experience (naive vs. experienced (odds ratio [OR], 3.722; 95% CI, 1.487 - 9.316; P = .005), DMT Rout (oral vs. injectable; OR, 0.974; 95% CI, 0.952 - 0.995; P = .017), and Global Satisfaction; OR, 0.950; 95% CI, 0.926 - 0.975; P = <0.001)
Conclusions
In patients with MS sampled from KFMC’s Data Base, medication beliefs was not significantly associated with DMT adherence while the Global satisfaction was significantly associated with DMT adherence. Based on significant predictors, patients taking injectable DMTs, and patients with previous experience with another DMT(s) are at higher risk for no adherence. Future research is warranted to assess relationships between variables in more diverse MS populations.