Author Of 1 Presentation
P1106 - Postprandial somnolence in multiple sclerosis: the invisible is real. (ID 1469)
Abstract
Background
Some invisible symptoms of multiple sclerosis (MS) are more important to the individual’s sense of wellbeing than physical disability. Patients with MS (pwMS) may be more sensitive to the effects of postprandial somnolence (PPS) than the general population, but this has not been confirmed yet.
Objectives
To evaluate the association between MS and PPS. To evaluate the impact of lifestyle modifications on the improvement of PPS in pwMS.
Methods
A cross-sectional study was conducted among pwMS (n=107) and age- and sex-matched people without MS (n=107) at The Royal London Hospital, London, UK. Participants were asked to complete an online survey including demographics, a description of their most recent meal and the Stanford Sleepiness Scale (SSS) one hour after lunch. A chi-square test was used to assess group differences for binary and nominal variables. For ordinal variables, a Mann-Whitney U test was used. Kendall's tau correlation test was performed to measure the correlation between MS and SSS scores.
Results
64.2% of pwMS subjectively reported PPS, compared to 49.5% of people without MS (p=0.044). The median SSS for pwMS was 3 (IQR 2-5) and for people without MS was 2 (IQR 2-3) (p=0.009). There was minimal association between patient characteristics and PPS. Symptoms of PPS were improved by eating smaller portions (p<0.001), consuming less carbohydrates (p<0.001), consuming less fat (p=0.026) and by exercising (p=0.008).
Conclusions
PwMS suffer from PPS more than people without MS and symptoms can be improved through dietary adjustments. These findings can be adopted in clinical practice to manage PPS in pwMS.
Presenter Of 1 Presentation
P1106 - Postprandial somnolence in multiple sclerosis: the invisible is real. (ID 1469)
Abstract
Background
Some invisible symptoms of multiple sclerosis (MS) are more important to the individual’s sense of wellbeing than physical disability. Patients with MS (pwMS) may be more sensitive to the effects of postprandial somnolence (PPS) than the general population, but this has not been confirmed yet.
Objectives
To evaluate the association between MS and PPS. To evaluate the impact of lifestyle modifications on the improvement of PPS in pwMS.
Methods
A cross-sectional study was conducted among pwMS (n=107) and age- and sex-matched people without MS (n=107) at The Royal London Hospital, London, UK. Participants were asked to complete an online survey including demographics, a description of their most recent meal and the Stanford Sleepiness Scale (SSS) one hour after lunch. A chi-square test was used to assess group differences for binary and nominal variables. For ordinal variables, a Mann-Whitney U test was used. Kendall's tau correlation test was performed to measure the correlation between MS and SSS scores.
Results
64.2% of pwMS subjectively reported PPS, compared to 49.5% of people without MS (p=0.044). The median SSS for pwMS was 3 (IQR 2-5) and for people without MS was 2 (IQR 2-3) (p=0.009). There was minimal association between patient characteristics and PPS. Symptoms of PPS were improved by eating smaller portions (p<0.001), consuming less carbohydrates (p<0.001), consuming less fat (p=0.026) and by exercising (p=0.008).
Conclusions
PwMS suffer from PPS more than people without MS and symptoms can be improved through dietary adjustments. These findings can be adopted in clinical practice to manage PPS in pwMS.