Author Of 3 Presentations
P0804 - Dual task during walking in patients with Multiple Sclerosis: cognitive or motor interference?
(ID 1453)
Abstract
Background
Impairment in dual task (DT) activities has been previously reported in patients with multiple sclerosis (MS). Most studies analyze DT during walking whether incorporating a second cognitive or motor task. More research is needed in order to define what type of task (cognitive or motor) determines the severity of the interference produced in the DT.
Objectives
1) To compare DT performance between patients with MS and healthy controls. 2) To analyze DT performance according to the type of task that interferes (cognitive or motor).
Methods
94 patients with relapsing remitting MS and 25 healthy controls (HC) were included. Patient age: 38.61 ± 11.44; Education: 13.26 ± 3.77; Disability (EDSS): 2.13 ± 1.16; Evolution: 9.66 ± 8.96. HC age: 34.00 ± 14.25; Education: 14.50 ± 2.65. Measuring instruments: Clinical variables: EDSS; Fatigue severity scale; Beck Depression Inventory II. Cognitive variables: BICAMS battery; DT: cognitive-motor task (walking while performing cognitive task) and motor-motor task (walking while performing motor task). The difference between performance in the single task and in the dual task situation was obtained. Parametric and non-parametric statistics were used, to define significance a value of p <0.05 was accepted
Results
: patients and HC did not differ in age (p = 0.12) and education (p = 0.11). Patient presented poorer performance than HC in cognitive-motor DT (U: between 334.50 and 238.50; p <0.05) but not in motor-motor DT (p> 0.05). Patients with EDSS> 2, presented lower performance than the controls in both types of task (p <0.05). The motor-motor task differentiated patients with EDSS <y> 2 (t: 2.85 and 3.51; p <0.05).
Conclusions
MS patients show impairment in the DT performance when the second task is cognitive. In patients with greater disability, alteration is found in both DT. Studying patient’s performance in DT allows a more ecological approach to their symptoms in order to directly intervene in daily life alterations.
P0819 - Perceived Social Support in Multiple Sclerosis: Impact on patient’s quality of life. (ID 1241)
Abstract
Background
Social support plays an extremely important role in treatment and evolution of patients with multiple sclerosis (MS). However, there are scarce data that describes the size and quality of social network in MS patients, as well as its impact on their quality of life.
Objectives
(a) to analyze differences in perceived social support (PSS) between MS patients and healthy controls. (b) to study the associations between PSS and clinical and health-related quality of life (HRQoL) variables in MS patients, and (c) to analyze the influence of PSS on HRQoL.
Methods
151 MS patients and 89 healthy controls (HC) were studied. HC: Age: 42.01±12.25 years; Education: 14.60±2.44 years; Patients: Age: 41.46±9.97; Education:14.05±3.26 years; EDSS:2.88±2.10; Disease evolution:12.46±10.07 years. Instruments: PSS: MOS (Medical Outcomes Study Social Support Survey); Clinical Variables: EDSS, Fatigue Scale (FSS); Depression Inventory (BDI-II); HRQoL: MusiQol. Parametric and non-parametric statistics were used, significance p value<0.05.
Results
Patients presented lower scores than HC in global score of PSS (t(238)=- 1.99, p=0.04) and in each functional dimension (t(238)=between-2.59 and -2.09, p<0.05). Associations were found between PSS with depression and fatigue (r = between-0.20 and -0.29, p <0.05) and with the different dimensions of the MusiQol (r = between-0.18 and 0.48, p <0.05). In multiple regression analysis, the four models tested contributed significantly to the explained variance of HRQoL (between 41 and 47%). The model constituted with emotional/informational support explained the greatest variation of HRQoL (47%).
Conclusions
Patients with MS perceive a decrease in their social support impacting on their quality of life. This should be considered for a better therapeutic approach.
P1030 - Exploring factors that impact on quality of life: coping strategies. (ID 1545)
Abstract
Background
Coping is conceived as the cognitive and behavioral efforts of a patient to adjust to disease and it may impact quality of life.
Objectives
We proposed to study the association between coping styles used by patients with Multiple Sclerosis (MS) and health-related quality of life (HRQoL).
Methods
90 MS patients (RRMS 95.56%; PPMS 2.22%; SPMS 2.22%) were included. 65.56% female; mean age: 40.97±12.85 years; education:13.46±3.93 years; Expanded Disability Status Scale (EDSS): 2.48±1.79; disease evolution 10.76±9.72. Outcomes measures: Argentine adaptation of the Inventory of coping responses CRI-A for adults; EDSS; Beck Depression Inventory; Fatigue Severity Scale and MS International Quality of Life questionnaire. Only the coping styles and the strategies that provided significant results were detailed: Problem-focused coping style, their strategies Positive Reappraisal (PR) and Seeking alternative Rewards (SR); Emotion-focused coping style and their strategy Emotional Discharge (ED).
Results
Significant correlations were found between coping styles, their strategies and HRQoL dimension. Patients with closer relationships with family (r=0.23) and friends (r=0.24), and better sentimental and sexual lives (r=0.32) obtained higher scores in problem-focused coping style, adopting an active role against the stressor. Positive and significant correlations were also found between the PR strategy and total HRQoL (r=0.21), relationship with friends (r=0.23) and sexual and sentimental life (r=.30). Furthermore, a significant positive relation was established between the SR strategy and the dimensions of activities of daily living (r= 0.25), relationships with friends (r=0.31), sentimental and sexual life (r= 0.33) and total HRQoL (r=0.28). On the other hand, patients who obtained higher scores in emotion-focused coping style reported lower HRQoL (r=-0.23), lower psychological well-being (r=-0.39) and lower scores in the dimensions of quality of life related to coping (r=-0.43) and the feeling of rejection (r=-0.23). The ED strategy was negatively correlated with total HRQoL (r=-0.29) and psychological well-being (r=-0.50).
Conclusions
The results obtained indicate that coping styles should be considered to improve the HRQoL and to study possible interventions in coping skills.
Presenter Of 1 Presentation
P1012 - Coping Strategies: Seeking personalized care in Multiple Sclerosis. A patient reported measure– Coping Responses Inventory. (ID 1548)
Abstract
Background
Background: Coping is defined as a set of cognitive and behavioral efforts made to master stressful specific demands. Adaptation to chronic diseases, such as Multiple Sclerosis (MS), depends on the effectiveness of coping.
Objectives
Objective: to assess the psychometric properties of the Coping Responses Inventory (CRI-A) in the subpopulation of MS patients, to verify the transferability of the instrument, which has already been validated in the Argentine general population and to assess the analysis of external criterion validity, by studying the relationship between coping styles and physical disability, depression, fatigue and years of evolution of the disease and clinical course.
Methods
Methods: 90 MS patients were included; Outcomes measures: CRI-A Inventory, Expanded Disability Status Scale (EDSS), Beck Depression Inventory and Fatigue Severity Scale.
Results
Results: 95.56% of the patients had Relapsing-Remitting MS (RRMS), 2.22% Primary-Progressive MS (PPMS), and 2.22% Secondary-Progressive MS (SPMS). The group comprised 59 women (65.56%), with a mean age of 40.97±12.85 years and mean education of 13.46±3.93 years. The group shows a mean of 13.92±10.45 for depression, 3.77±1.72 for fatigue, 10.76±9.72 for disease evolution and 2.48±1.79 for disability. CRI-A Inventory maintains the psychometric properties of the Argentine general population in the MS subpopulation, with adequate validity and reliability. The respondents most frequently utilized a problem focused coping style. A significant positive correlation was found between the problem-focused coping style and education (r= 0.31). As regards clinical variables, significant positive correlations were found between the emotion‑focused coping style and fatigue (r=0.21) and depression (r= 0.43). Nevertheless, when studying each of the 8 coping strategies on their own, a significant positive correlation was found between 3 strategies of the emotion-focused coping style: avoidance (r=0.27), acceptance (r=0.27) and emotional discharge (r=0.42), and depression. In addition, the seeking alternative rewards strategy was linked to the disease evolution and fatigue (r= 0.24/-0.22).
Conclusions
Conclusions: The results demonstrate the transferability of the CRI-A of the general population of Argentina in the subpopulation of patients with MS. Patients with MS develop more problem-focused strategies.