Hospital Sant Joan de Deu
Pediatrics

Author Of 1 Presentation

Reproductive Aspects and Pregnancy Poster Presentation

P1140 - Study of anthropometric measures of newborns of MS mothers (ID 713)

Speakers
Presentation Number
P1140
Presentation Topic
Reproductive Aspects and Pregnancy

Abstract

Background

There are some controversies about the neonatal anthropometric measures of infants born to MS mothers. Some studies reported a reduction of the head circumference at birth of newborns of MS mothers, which has been associated with developmental delay in other pathologies.

Objectives

To compare head circumference (HC) at birth of newborns of MS mothers with head circumference of newborns of healthy mothers.

Methods

Prospective study in pregnant women and their offsprings. Gestational age and head circumference were analyzed applying 3 different references standards.

Results

We studied 76 women and 96 pregnancies, 90 deliveries and 6 still ongoing. Mean maternal age was 35 ±4 years.

We studied 92 newborns and after excluding preterm and posterm, we analyzed neonatal head circumference of 83 term newborns, 45 girls and 38 boys and mean gestational age of 39.4 ±1 weeks.

Male infants mean HC at birth was 34.8 cm ±1,28 compared with WHO 50th percentile reference of 34.5 cm (p 0.07). Female mean birth HC was 34.6 cm ±0,99, larger than WHO reference of 33.9 cm (p <0.05).

Applying worldwide, the most accepted charts in neonatal centers, Olsen et al. growth curves, that include gender-specific HC-for age curves from infants aged 22 to 42 weeks at birth, we found 9 male infants born at 38 weeks with a mean HC of 34.4 cm ±1.16 the same as the Olsen charts (OC); 13 born at 39 weeks HC mean: 35.3 cm ±1.47 larger than OC (34.6 cm) p 0.12; 8 born at 40 weeks and 6 at 41 weeks HC mean: 34.8 cm ±1.00 and 35.0 cm ±1.55 respectively, the same as the OC in both ages. Analyzing female infants we found; 12 female infants born at 38 weeks with a mean HC of 34.4 cm ±0.76 larger than OC (33.7 cm) p 0.08; 10 born at 39 weeks HC mean: 34.7 cm ±1.11 larger than OC (34.0 cm) (p 0.07); 10 born at 40 weeks HC mean: 34.6 cm ±0.91 compared to 34.3 in OC (p 0.32) and 6 at 41w HC mean: 35.2cm ±0.94 larger than OC charts (34.5 cm) p 0.11.

Spanish pediatric centers usually used the charts of the Orbegozo Foundation,as standard reference. Comparing our cohort and 50th percentile of the Orbegozo Foundation (35.19 cm ±1.14 for male and 34.48 cm ±1.16 for female) there were no significant findings.

Conclusions

We hence conclude that there were no statistically significant differences in the mean head circumference at birth in newborns of MS mothers compared to different references standard. It is worth highlighting that in order to compare anthropometric measurements in newborns it is crucial to apply standards references that include sex, gestational age and if possible national growth standards to avoid bias, which ultimately are lacking in the WHO standards.

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