Hospital Universitari de Bellvitge
Department of Neurology

Author Of 1 Presentation

Clinical Outcome Measures Poster Presentation

P0029 - Assessment of Multiple Sclerosis Severity Score and Age-Related Multiple Sclerosis Severity Score as health indicators in a population-based cohort (ID 447)

Speakers
Presentation Number
P0029
Presentation Topic
Clinical Outcome Measures

Abstract

Background

Persons with multiple sclerosis (MS) present varying degrees of disability throughout the course of the disease. The Multiple Sclerosis Severity Score (MSSS) and the Age-Related Multiple Sclerosis Severity Score (ARMSSS) adjust the score obtained in the Expanded Disability Status Scale (EDSS) according to disease duration and age, respectively. These measures could be useful as health outcome indicators.

Objectives

The aim of this study was to describe the severity of MS in our health district and assess MSSS and ARMSSS consistency over time.

Methods

Patients diagnosed with MS according to 2010 McDonald criteria, with at least one year of disease duration and followed up in our MS unit within the previous 18 months were selected. Sex, age at onset, disease duration, clinical course, age and irreversible EDSS at last follow-up visit were collected. MSSS and ARMSSS were calculated. Our cohort was studied twice, in 2017 and 2020 to assess the consistency of both instruments.

Results

One hundred and seventy-seven patients were included in 2017, and 208 in 2020. Prevalence of MS in our health district was 90 and 105 per 100,000 inhabitants, respectively, in line with the expected prevalence. Median MSSS and ARMSSS were similar in both study years. In 2017, median MSSS was 1.77 (IQR 0.76-4.28) and ARMSSS was 2.9 (IQR 1.47-5.72). In 2020, median MSSS was 2.03 (IQR 0.82-4.36) and ARMSSS was 2.93 (IQR 1.51-5.56).

Conclusions

According to MSSS and ARMSSS, our cohort presented mild disease, and the results were consistent at both time points. MSSS and ARMSSS may be reliable health outcome measures.

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Presenter Of 1 Presentation

Clinical Outcome Measures Poster Presentation

P0029 - Assessment of Multiple Sclerosis Severity Score and Age-Related Multiple Sclerosis Severity Score as health indicators in a population-based cohort (ID 447)

Speakers
Presentation Number
P0029
Presentation Topic
Clinical Outcome Measures

Abstract

Background

Persons with multiple sclerosis (MS) present varying degrees of disability throughout the course of the disease. The Multiple Sclerosis Severity Score (MSSS) and the Age-Related Multiple Sclerosis Severity Score (ARMSSS) adjust the score obtained in the Expanded Disability Status Scale (EDSS) according to disease duration and age, respectively. These measures could be useful as health outcome indicators.

Objectives

The aim of this study was to describe the severity of MS in our health district and assess MSSS and ARMSSS consistency over time.

Methods

Patients diagnosed with MS according to 2010 McDonald criteria, with at least one year of disease duration and followed up in our MS unit within the previous 18 months were selected. Sex, age at onset, disease duration, clinical course, age and irreversible EDSS at last follow-up visit were collected. MSSS and ARMSSS were calculated. Our cohort was studied twice, in 2017 and 2020 to assess the consistency of both instruments.

Results

One hundred and seventy-seven patients were included in 2017, and 208 in 2020. Prevalence of MS in our health district was 90 and 105 per 100,000 inhabitants, respectively, in line with the expected prevalence. Median MSSS and ARMSSS were similar in both study years. In 2017, median MSSS was 1.77 (IQR 0.76-4.28) and ARMSSS was 2.9 (IQR 1.47-5.72). In 2020, median MSSS was 2.03 (IQR 0.82-4.36) and ARMSSS was 2.93 (IQR 1.51-5.56).

Conclusions

According to MSSS and ARMSSS, our cohort presented mild disease, and the results were consistent at both time points. MSSS and ARMSSS may be reliable health outcome measures.

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