Flore Zaba, Côte d'Ivoire

university Félix Houphouet Boigny Abidjan Microbiologie

Presenter of 1 Presentation

 Conference Calendar

INCREASE OF PNEUMOCOCCAL UNTYPEABLE STRAINS IN COTE D’IVOIRE (ID 1238)

Session Name
Clinical Sciences - Disease Burden in Infants, Children/Youth, and Adults
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Author Of 3 Presentations

 Conference Calendar

PAEDIATRICS MENINGITIS SURVEILLANCE IN CÔTE D’IVOIRE AND USE OF IB-VPD/PBM TO MONITOR PCV IMPACT (ID 201)

Session Name
Vaccines - Impact of Vaccine programs and Serotype Replacement
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Abstract

Background

National paediatric bacterial meningitis (PBM) surveillance began in 2002 in Côte d’Ivoire. This surveillance is under the supervision of the immunization program. The aim of this work was to describe the PBM surveillance in Côte d’Ivoire and use of IB-VPD/PBM to monitor PCV impact.

Methods

The paediatric service notifies suspected cases, collect and send the CSF samples to the laboratory. The laboratory receives and analyse CSF and do the management of data. The technical, logistical and financial support were provided by WHO, CDC and Regional Laboratory of GAMBIA MRC. The national immunization program provided feedback to central level.

Results

From January 2002 to December 2019, 7769 CSF samples were submitted to the sentinel site laboratory. Of these samples, 263(3.39%) gave a positive culture with bacterial growth. S. pneumoniae, 50.57% (133 /263) H. influenzae 30.08 (87 /263) and 5.7 % (15/263) N. meningitidies over all the years of monitoring. Pneumococcal conjugate vaccine (PCV) serotypes, 5, 18C, 19F and 6A/B were identified post-vaccine introduction.

Conclusions

This surveillance generated data used for to evidence of disease burden, and advocacy to introduce in routine immunization Pneumococcal conjugate vaccine -13 (PCV 13) in 2014.

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RESISTANCE OF STREPTOCOCCUS PNEUMONIAE STRAINS TO ANTIBIOTICS IN ABIDJAN, COTE D'IVOIRE FROM 2009 - 2018: DATABASE ANALYSIS (ID 1070)

Session Name
Basic Sciences - Conventional and Molecular Microbiology
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Abstract

Background

Antimicrobial resistance of S. pneumoniae is described worldwide and is increasing. The situation of this resistance in some countries in Africa like Cote d'Ivoire remains unclear.We aim to describe the resistance profiles of S. pneumoniae strains against antibiotics tested in a reference laboratory in Abidjan.

Methods

We conducted secondary data analysis and extracted data from Laboratory database containing all the results of the antibiograms performed at Pasteur Institute of Cote d'Ivoire from 2009-2018. The analysis was done using Epi info software version 7. 2. and exported to Microsoft Excel removing duplicates and presented the results into frequencies and proportions.

Results

The analysis involved 150 human strains isolated from 59. 3% of cerebrospinal fluid cases. The age group 0 to 2 years was the highest 52. 8%. Concerning the resistance of antibiotic, 27. 02% showing decreased susceptibility to beta-lactam antibiotics and 23. 2% showing resistance to Gentamycin. For Erythromycin and Levofloxacin, the prevalence of bacteria resistant to these two antibiotics was 17.2% and 13. 6% respectively.

Conclusions

Antibiotic resistance of S pneumoniae strains exists and it is important in Côte d'Ivoire, hence the need for surveillance.

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INCREASE OF PNEUMOCOCCAL UNTYPEABLE STRAINS IN COTE D’IVOIRE (ID 1238)

Session Name
Clinical Sciences - Disease Burden in Infants, Children/Youth, and Adults
Presenter
Authors