The Louisville Pneumonia Study Group, United States of America
University of Louisville School of Medicine Division of Infectious DiseasesAuthor Of 7 Presentations
S. PNEUMONIAE SEROTYPES IN HOSPITALIZED PATIENTS WITH SEVERE PNEUMOCOCCAL PNEUMONIA AND CLINICAL FAILURE (ID 807)
- Julio Ramirez, United States of America
- Stephen Furmanek, United States of America
- Senen Pena, United States of America
- Ruth Carrico, United States of America
- Forest Arnold, United States of America
- Ronika Alexander, United States of America
- Kimbal D. Ford, United States of America
- Sharon L. Gray, United States of America
- Luis Jodar, United States of America
- Raul Isturiz, United States of America
- The Louisville Pneumonia Study Group, United States of America
ANNUAL NUMBER OF ADULTS HOSPITALIZED WITH PNEUMOCOCCAL PNEUMONIA IN THE UNITED STATES (ID 473)
- Julio Ramirez, United States of America
- Stephen Furmanek, United States of America
- Senen Pena, United States of America
- Ruth Carrico, United States of America
- Forest Arnold, United States of America
- Ronika Alexander, United States of America
- Kimbal D. Ford, United States of America
- Sharon L. Gray, United States of America
- Luis Jodar, United States of America
- Raul Isturiz, United States of America
- The Louisville Pneumonia Study Group, United States of America
IMPACT OF MICROBIOLOGICAL WORKUP ON THE INCIDENCE OF HOSPITALIZATIONS DUE TO PNEUMOCOCCAL PNEUMONIA (ID 809)
- Julio Ramirez, United States of America
- Stephen Furmanek, United States of America
- Senen Pena, United States of America
- Ruth Carrico, United States of America
- William Mattingly, United States of America
- Ronika Alexander, United States of America
- Kimbal D. Ford, United States of America
- Sharon L. Gray, United States of America
- Luis Jodar, United States of America
- Raul Isturiz, United States of America
- The Louisville Pneumonia Study Group, United States of America
EARLY AND LATE MORTALITY OF ADULTS HOSPITALIZED WITH PNEUMOCOCCAL PNEUMONIA IN THE UNITED STATES (ID 797)
- Julio Ramirez, United States of America
- Stephen Furmanek, United States of America
- Senen Pena, United States of America
- Ruth Carrico, United States of America
- William Mattingly, United States of America
- Ronika Alexander, United States of America
- Kimbal D. Ford, United States of America
- Sharon L. Gray, United States of America
- Luis Jodar, United States of America
- Raul Isturiz, United States of America
- The Louisville Pneumonia Study Group, United States of America
Abstract
Background
The number of deaths due to pneumococcal pneumonia (PP) in the United States (U.S.) is not well defined. The objectives of this study were to define mortality of PP in the city of Louisville, Kentucky and to estimate the number of deaths in hospitalized patients with PP in the U.S.
Methods
In hospitalized patients with community-acquired pneumonia (CAP), urinary antigen detection of 24 S. pneumoniae serotypes (UAD-24) was performed. This UAD-24 study was nested in a prospective population-based cohort study of all adult residents in Louisville, hospitalized with CAP from 6/1/14 to 5/31/16. Louisville PP mortality was evaluated early (during hospitalization and at 30-days after hospitalization) and late (6-months and 1-year after hospitalization) and US number of deaths were estimated.
Results
A total of 708 patients with PP were evaluated. PP mortality was 3.7% during hospitalization, 8.2% at 30-days, 17.6% at 6-months, and 25.4% at 1-year. Number of deaths in the U.S. were: 8,323 (95%CI:5,468-12,091) during hospitalization, 18,619 (95%CI:14,231-23,711) at 30-days, 39,807 (95%CI:33,506-46,502) at 6 months, and 57,626 (95%CI:50,130-64,940) at 1-year.
Conclusions
In hospitalized patients, PP is associated with significant early and late mortality. Approximately 1 out of 4 hospitalized adult patients with PP will die within 1-year.
EFFECTIVENESS OF 23-VALENT PNEUMOCOCCAL POLYSACCHARIDE VACCINE (PPV-23) IN THE PREVENTION OF HOSPITALIZATIONS DUE TO VACCINE-TYPE PNEUMOCOCCAL PNEUMONIA (ID 811)
- Julio Ramirez, United States of America
- Stephen Furmanek, United States of America
- Senen Pena, United States of America
- William Mattingly, United States of America
- Forest Arnold, United States of America
- Tim Wiemken, United States of America
- Ruth Carrico, United States of America
- The Louisville Pneumonia Study Group, United States of America
LOW-INCOME LEVEL IS ASSOCIATED WITH HOSPITALIZATION DUE TO PNEUMOCOCCAL PNEUMONIA (ID 800)
- Julio Ramirez, United States of America
- Stephen Furmanek, United States of America
- Senen Pena, United States of America
- Ruth Carrico, United States of America
- Tim Wiemken, United States of America
- Ronika Alexander, United States of America
- Kimbal D. Ford, United States of America
- Sharon L. Gray, United States of America
- Luis Jodar, United States of America
- Raul Isturiz, United States of America
- The Louisville Pneumonia Study Group, United States of America
ASSOCIATION OF S. PNEUMONIAE SEROTYPES WITH MYOCARDIAL INFARCTION AND OTHER CARDIAC EVENTS IN HOSPITALIZED PATIENTS WITH PNEUMOCOCCAL PNEUMONIA (ID 805)
- Julio Ramirez, United States of America
- Stephen Furmanek, United States of America
- Senen Pena, United States of America
- Ruth Carrico, United States of America
- Paula Peyrani, United States of America
- Ronika Alexander, United States of America
- Kimbal D. Ford, United States of America
- Sharon L. Gray, United States of America
- Luis Jodar, United States of America
- Raul Isturiz, United States of America
- The Louisville Pneumonia Study Group, United States of America