BURDEN OF DISEASE ASSOCIATED WITH PNEUMONIA AND INVASIVE PNEUMOCOCCAL DISEASE (IPD) IN INDIVIDUALS AGED 15 YEARS AND ABOVE IN SPAIN
The available burden of disease (BoD) studies in pneumococcal disease in Spain are limited to analyzing data restricted to specific geographical regions. This study assessed the clinical burden associated with streptococcus pneumoniae in Spain.
A retrospective study was conducted using Conjunto Mínimo de Datos-Hospitalización (CMBD-H), a publicly available database provided by the Spanish Ministry of Health covering approximately 90% of hospitalization episodes.
The study population consisted of individuals aged 15 years and older who were hospitalized with a diagnosis of pneumonia, bacteremia and meningitis due to Streptococcus Pneumoniae in 2015.
In 2015, the estimated burden of pneumococcal disease potentially avoidable through vaccination represented 10,274 inpatient admissions including 9,015 cases of pneumonia, 309 cases of meningitis and 950 cases of septicemia. Additionally, 867 deaths were registered during these hospitalization episodes. The information available in CMBD-H only captures individual hospitalization episodes and cannot capture per patient hospitalization, therefore it could be used as an approximation to estimate disease incidence, but not real incidence, which is a limitation of the study.
Pneumococcal disease still contributes to substantial morbidity and mortality among individuals aged 15 years and older in Spain.