L. Lenoir (Montréal, CA)

Emovi Inc.

Presenter Of 1 Presentation

Poster Osteoarthritis

P154 - Biomechanical Markers Association with Clinical Outcome Measures in Osteoarthritis Patients; Data from Knee Kinesiography Exam

Presentation Topic
Osteoarthritis
Date
13.04.2022
Lecture Time
09:30 - 09:30
Room
Exhibition Foyer
Session Name
7.3 - Poster Viewing / Coffee Break / Exhibition
Session Type
Poster Session
Disclosure
L.Lenoir, Emovi Inc., Employee. P.Ranger, Bioventus, Consultant, Sanofi-Aventis, Consultant, Smith & Nephew, Consultant. N.Mezghani, Emovi Inc., Grant Research Support. N. Hagemeister, Emovi Inc., Grant Research Support.

Abstract

Purpose

Objective and patient-reported outcome measures are used to assess functional limitations and symptoms in patients with knee osteoarthritis (OA). While biomechanical markers from a kinematic assessment are known to be more associated with clinical measures compared to static mechanical parameters, the variability between tools to quantify them makes it difficult to generalize these associations. This study aimed at synthesizing the associations in knee OA patients between clinical measures and dynamic biomechanical markers assessed through a knee kinesiography exam.

Methods and Materials

A comprehensive review was conducted to identify studies within the RESEARCHGATE and MEDLINE databases. The knee kinesiography exam evaluates the three-dimensional knee function in a clinical setting while patient is walking on a commercial treadmill. Using the KneeKG system, it provides accurate knee motion measures when compared to fluoroscopy images. This validated medical device also allows high repeatability and reliability for joint angles.

Results

Five outcome measures categories were identified based on retained studies: 1) Knee Injury and Osteoarthritis Outcome Score (KOOS) or Western Ontario and McMaster Universities Arthritis Index (WOMAC), 2) objective physical function (stair ascent and descent time, Timed-up and go test), 3) Oxford Knee Score (OKS), 4) global health status (frailty index), and 5) quadriceps and hamstring strength. Significant associations (p<0.05) between dynamic biomechanical markers and patient’s outcome measures are displayed in Table 1.

table 1 significant associations between dynamic biomechanical markers and patient’s outcomes .png

Conclusion

Review confirms link between biomechanical markers and clinical outcome measures. Results suggest that greater amplitudes of flexion-extension and tibial rotation (during loading phase) are largely associated with better outcomes measures in knee OA patients. Greater flexion angle at heel strike (dynamic flexion contracture) and varus-valgus range of motion throughout the gait cycle are associated with worst outcomes. This review helped identify modifiable biomechanical markers that should be addressed through conservative treatment to potentially impact clinical outcome measures in non-surgical patients or post-surgery.

Collapse

Presenter Of 1 Presentation

Osteoarthritis

P154 - Biomechanical Markers Association with Clinical Outcome Measures in Osteoarthritis Patients; Data from Knee Kinesiography Exam

Abstract

Purpose

Objective and patient-reported outcome measures are used to assess functional limitations and symptoms in patients with knee osteoarthritis (OA). While biomechanical markers from a kinematic assessment are known to be more associated with clinical measures compared to static mechanical parameters, the variability between tools to quantify them makes it difficult to generalize these associations. This study aimed at synthesizing the associations in knee OA patients between clinical measures and dynamic biomechanical markers assessed through a knee kinesiography exam.

Methods and Materials

A comprehensive review was conducted to identify studies within the RESEARCHGATE and MEDLINE databases. The knee kinesiography exam evaluates the three-dimensional knee function in a clinical setting while patient is walking on a commercial treadmill. Using the KneeKG system, it provides accurate knee motion measures when compared to fluoroscopy images. This validated medical device also allows high repeatability and reliability for joint angles.

Results

Five outcome measures categories were identified based on retained studies: 1) Knee Injury and Osteoarthritis Outcome Score (KOOS) or Western Ontario and McMaster Universities Arthritis Index (WOMAC), 2) objective physical function (stair ascent and descent time, Timed-up and go test), 3) Oxford Knee Score (OKS), 4) global health status (frailty index), and 5) quadriceps and hamstring strength. Significant associations (p<0.05) between dynamic biomechanical markers and patient’s outcome measures are displayed in Table 1.

table 1 significant associations between dynamic biomechanical markers and patient’s outcomes .png

Conclusion

Review confirms link between biomechanical markers and clinical outcome measures. Results suggest that greater amplitudes of flexion-extension and tibial rotation (during loading phase) are largely associated with better outcomes measures in knee OA patients. Greater flexion angle at heel strike (dynamic flexion contracture) and varus-valgus range of motion throughout the gait cycle are associated with worst outcomes. This review helped identify modifiable biomechanical markers that should be addressed through conservative treatment to potentially impact clinical outcome measures in non-surgical patients or post-surgery.

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