I have a broad background in molecular and regenerative medicine. My work was the first-of-kind study on healthy objects and therefore has led to the understanding of how IRF5 genetic risk variants drive an SLE immune-phenotype in healthy individuals. This finding provides evidence for uncovering the origin of predisposition to immune cell dysfunction; which in turn leads to autoimmune diseases; including SLE. I have also demonstrated that IRF5 suppresses breast cancer progression and metastasis. I and my colleagues identified intratumoral IRF5 as a critical molecular switch that controls the functional programming of a breast tumor and its microenvironment to either initiate or prevent metastatic colonization through the regulation of the composition and secretion of extracellular vesicles. Outcomes from this research provides new strategies for the prevention and treatment of metastatic disease. In March 2019; I started working in the field of orthopedic regenerative medicine with a specialty in biologics and scaffolds for tissue regeneration. I have identified and demonstrated in my study a novel and powerful cell-free therapy for osteoarthritis (OA). I am also working on comparison of several methods derived from autologous chondrocyte implantation (ACI); in order to develop a more advanced cartilage repair technique using cartilage tissue.