P119 - Defining Clinically Significant Outcomes After Meniscal Allograft Transplantation at Minimum 5-Year Follow-up
- K. Wagner (Chicago, US)
- K. Wagner (Chicago, US)
- J. Kaiser (Chicago, US)
- Z. Meeker (Chicago, US)
- N. Condron (Chicago, US)
- S. Patel (Kalamazoo, US)
- R. Gilat (Be'er Ya'akov, IL)
- D. Knapik (, US)
- A. Yanke (Chicago, US)
- B. Cole (Chicago, US)
Abstract
Purpose
To define values and variables predictive for achieving clinically significant outcomes (CSO), including minimal clinically important difference (MCID), substantial clinical benefit (SCB) and patient acceptable symptomatic state (PASS), in patients who underwent meniscal allograft transplant (MAT) at a minimum 5-year follow up.
Methods and Materials
International Knee Documentation Committee (IKDC), Lysholm, and Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales were collected pre-operatively and at most recent follow up for patients who underwent MAT from 1999-2016. A distribution-based approach was used to calculate MCID, while an anchor-based approach was used to calculate SCB and PASS. Logistic regression was performed to determine factors associated with CSO achievement.
Results
102 patients were identified at an average follow-up of 9.7 years (± 3.8 years) and CSO thresholds were determined (Figures 1, 2; Tables 1, 2). Reduced odds of achieving MCID, PASS, and SCB were associated with female sex and increased preoperative scores. Additionally, reduced odds of achieving PASS was associated with worker’s compensation (WC) status, while increased body mass index (BMI) reduced odds of achieving SCB for KOOS Activities of Daily Living (ADL).
| Age at surgery | 28.64±9.4 |
| Male sex | 47 |
| BMI | 25.87±4.2 |
| WC | 10 |
| Concomitant Procedures | |
| Osteochondral allograft transplantation | 43 |
| Anterior cruciate ligament reconstruction | 10 |
| None | 27 |
| MCID | |
| Lysholm | 9.5 |
| IKDC | 12.0 |
| KOOS | |
| Pain | 10.2 |
| Symptoms | 11.3 |
| ADL | 10.8 |
| Sport | 14.8 |
| Quality of Life (QOL) | 13.9 |
| PASS | |
| Lysholm | 77.0 |
| IKDC | 62.6 |
| KOOS | |
| Pain | 79.2 |
| Symptoms | 62.5 |
| ADL | 90.4 |
| Sport | 32.5 |
| QOL | 46.9 |
| SCB | |
| Lysholm | 32.5 |
| IKDC | 18.3 |
| KOOS | |
| Pain | 15.3 |
| Symptoms | 16.1 |
| ADL | 13.7 |
| Sport | 40.5 |
| QOL | 37.2 |
Conclusion
At a minimum of 5-year follow-up, female sex, higher preoperative survey scores, increased BMI and WC status are associated with failure to achieve CSOs following MAT.