Poster Joint Specific Cartilage Repair

P097 - Injectable Scaffold with Microfracture Using the AMIC Technique: A Prospective Cohort Study

Presentation Topic
Joint Specific Cartilage Repair
Date
13.04.2022
Lecture Time
09:30 - 09:30
Room
Exhibition Foyer
Session Name
7.3 - Poster Viewing / Coffee Break / Exhibition
Session Type
Poster Session
Speaker
  • G. Bong (Singapore, SG)
Authors
  • G. Bong (Singapore, SG)
  • Y. Lee (Singapore, SG)
Disclosure
Y.H.L. Dave, Smith and Nephew, Education grant to institution, Speaker fees to individual, Travel grant Y.H.L. Dave, Depuy Mitek, Education grant to institution, Speaker fees to individual, Travel grant Y.H.L. Dave, Arthrex, Speaker fees to individual Y.H

Abstract

Purpose

Autologous matrix-induced chondrogenesis (AMIC) is a one-step surgical cartilage repair procedure involving insertion of a scaffold into the chondral defect after microfracture. BST-CarGel (Smith&Nephew, Watford, England) is an injectable chitosan-based scaffold which can more easily fill defects with irregular shapes and be used to treat vertical or roof chondral lesions. The aim of study is to evaluate the clinical outcomes of knee cartilage repair with microfracture surgery and injectable scaffold BST-CarGel using the AMIC technique at a minimum of 2 years.

Methods and Materials

A prospective study of patients undergoing cartilage repair with microfracture surgery and BST-CarGel at our institution from 2016 to 2019 was performed. Clinical outcomes were determined using two clinically-validated patient-reported questionnaires: Lysholm Knee Scoring System and Knee Injury and Osteoarthritis Outcome Score (KOOS). These questionnaires were administered prior to surgery and at a minimum of two years after surgery.

Results

A total of 21 patients were identified and recruited into the study. 31 cartilage defects were diagnosed and treated in 21 knees. These included horizontal lesions (eg. trochlear, lateral tibial plateau), vertical lesions (eg. medial femoral condyle, lateral femoral condyle) and inverted lesions (eg. patella). No complications or reoperations were seen in our study population. Over an average follow-up of 42.5 ± 8.55 months, there was an average improvement in Lysholm score of 25.8 ± 18.6 and an average improvement in KOOS score of 22.5 ± 15.0.

Conclusion

BST-CarGel with microfracture surgery using the AMIC technique is a safe and effective treatment for cartilage defects in the short to medium term.

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