G. Ode (New York, US)

Hospital for Special Surgery

Presenter Of 1 Presentation

Podium Presentation Cartilage /Cell Transplantation

16.4.6 - Predictors of Return to Athletic Activity Following Osteochondral Allograft Transplantation of the Knee

Presentation Number
16.4.6
Presentation Topic
Cartilage /Cell Transplantation
Lecture Time
12:00 - 12:09
Session Name
Session Type
Free Papers
Corresponding Author
Disclosure
No Significant Commercial Relationship

Abstract

Purpose

Osteochondral allograft (OCA) transplantation has demonstrated good functional outcomes and high rates of return to sport but in small cohort studies. This study reports the return to athletic activity and functional outcomes at minimum two years in a broader cohort of active patients who underwent knee OCA transplantation and reports predictive factors for return to activity.

Methods and Materials

Between 2000 – 2016, 163 active patients who underwent OCA transplantation within our institutional cartilage registry met inclusion criteria. ‘Active’ was defined as baseline pre-operative Cincinnati Sports Activity Scale (CSAS) of 3 or better (active at least 1-3x per month), running frequency of at least 1x/week or self-reported participation in sports at the time of injury. Patient characteristics and patient reported outcomes at yearly intervals (Knee Outcome Survey-Activities of Daily Living (KOS-ADL) score, International Knee Documentation Committee (IKDC) score, Marx Activity Rating Scale were reported.

Results

Patient characteristics are described in Table 1 . Mean age of the cohort was 39.4 +12.9 years with a male predominance (67%). At minimum two year follow-up, 144/163 patients (88.3%) returned to athletic activity (CSAS level 1-3), and 118/163 patients (76%) returned to the same level of activity or higher. Patient-reported outcomes are reported in Table 2. Mean change in KOS-ADL and IKDC at 2 years was 19 points and 25 points, respectively; which met the thresholds for minimal clinically important difference. Clinical predictors of return to activity on multivariate analysis were preoperative CSAS level 1 activity (participates 4+ days/week), and preoperative IKDC of >38 pts.

rta oca tables - icrs 1.jpg

rta oca tables - icrs 2.jpg

Conclusion

OCA results in high rates of return to athletic activity in active patients at 2 years. Clinically meaningful improvement in patient-reported outcome measures can be expected for most patients. High level of pre-operative function and activity were predictive of return to activity postoperatively.

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