Platelet Rich Plasma and Growth factors

P117 - Evaluation of clinical-functional results in patients diagnosed with rotator cuff injury infiltrated with platelet-rich plasma

Corresponding Author
Disclosure
No Significant Commercial Relationship
Presentation Topic
Platelet Rich Plasma and Growth factors
Poster Rating
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Abstract

Purpose

Purpose

The pathogenesis of rotator cuff lesions is due to their limited ability to regenerate due to the poor vascularization of the tendinous tissue. Infiltration with Platelet Rich Plasma (PRP) stimulates natural regeneration through the growth factors found in platelets. Infiltrations with PRP at sites of injury have recently gained popularity in the treatment of tendinopathies. Despite this popularity and increasing use in clinical settings, there is a limitation of well-designed studies that prove the effectiveness of this treatment in tendon injuries.

Methods and Materials

Material and Methods

In a retrospective cohort study, 56 patients were evaluated who had a diagnosis of partial rotator cuff injury in the period from April 2016 to July 2018, with an age range of 40 to 80 years, treated with 2 infiltrations of PRP every 2 months, to which 4 subsequent evaluations were made with the Constant-Murley test.

Results

Results

A total of 56 patients were obtained, of which 23 were men (30.8%) and 33 women (69.2%). A total of 4 Constant-Murley tests were performed at 0, 3, 6 and 12 months. The results obtained were favorable, with a statistical significance of P <0.0001, with a mean in the score of 53.42 initial, a mean of 66.08 at 3 months after the first application of PRP, an average of 73.35 after 6 months of the second application and an average of 76.27 after 12 months of the last application.

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Conclusion

Conclusion

The treatment of rotator cuff lesions with PRP is a safe and low-cost therapy, which improves tissue regeneration, reflected in clinical and functional improvement of patients.

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