Emmanouil Galanakis (Greece)

University of Crete Paediatrics

Author Of 2 Presentations

Welcome Words by the Meeting Chairs

Date
Tue, 10.05.2022
Session Time
18:45 - 19:40
Session Type
Plenary Symposium
Room
ALEXANDRA TRIANTI HALL
Lecture Time
18:45 - 18:55

CHARACTERISTICS OF CHILDREN HOSPITALIZED WITH MIS-C DURING THREE PANDEMIC WAVES IN GREECE

Date
Wed, 11.05.2022
Session Time
13:40 - 15:10
Session Type
Joint Symposium
Room
BANQUETING HALL
Lecture Time
14:50 - 14:58

Abstract

Backgrounds:

The Multisystem Inflammatory Syndrome in Children (MIS-C) is a rare but potentially severe complication of COVID-19.

Methods

This is a retrospective observational study of children aged <18 years hospitalized with MIS-C in 10 tertiary hospitals in Greece during three pandemic waves characterized by different SARS-CoV-2 variant: i. from August 2020 to January 2021 (EU1-B.1.177), ii. from February 2021 to July 2021 (Alpha-B.1.1.7) and iii. from August 2021 to December 2021 (Delta-B.1.617.2). The aim of the study was to document the incidence over time, clinical characteristics and outcome of children admitted with MIS-C in Greek hospitals during the COVID-19 pandemic.

Results:

table 1.jpg

In total, 119 patients were included, 91.6% (109/119) met the WHO criteria of MIS-C diagnosis: 26.9% (32/119), 39.5% (47/119) and 33.6% (40/119) were hospitalized during the 1st, 2nd, and 3rd study period, respectively. Demographic and clinical characteristics are shown in Table 1. No cases were found before October 2020. The incidence of MIS-C significantly decreased over the three waves from 3.3/1000 to 0.25/1000 confirmed COVID-19 cases (P <0.0001). No other significant difference was observed in the clinical manifestations and disease severity of children hospitalized with MIS-C over the three waves.

Conclusions/Learning Points:

This study indicates that the incidence of MIS-C may vary according to the predominant variant. Outcome remains favourable regardless of the variant leading to MIS-C. Larger studies are needed to clarify if clinical characteristics and/or disease severity may differ, as well.

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Presenter of 1 Presentation

Welcome Words by the Meeting Chairs

Date
Tue, 10.05.2022
Session Time
18:45 - 19:40
Session Type
Plenary Symposium
Room
ALEXANDRA TRIANTI HALL
Lecture Time
18:45 - 18:55

Moderator of 3 Sessions

Session Type
Plenary Symposium
Date
Tue, 10.05.2022
Session Time
17:15 - 18:45
Room
ALEXANDRA TRIANTI HALL
Session Type
Plenary Symposium
Date
Wed, 11.05.2022
Session Time
17:15 - 18:15
Room
ALEXANDRA TRIANTI HALL
Session Type
Special Session
Date
Thu, 12.05.2022
Session Time
10:00 - 11:30
Room
NIKOS SKALKOTAS HALL

Poster Author Of 6 e-Posters

AS07.b. Urogenital infections
AS13. COVID 19 and MIS-C

EP393 - COVID-19 INFECTION IN SPINAL MUSCULAR ATROPHY: A SINGLE CENTRE EXPERIENCE (ID 1166)

Session Name
0772 - E-Poster Viewing (ID 124)
My link to connect
Join Zoom Meeting https://us05web.zoom.us/j/4710218962?pwd=UWlTREJBMmltU080bjU3cC8xbjgyUT09 Meeting ID: 471 021 8962 Passcode: s6j7PR
AS04.a. Host-pathogen interaction

PD036 - SINGLE NUCLEOTIDE POLYMORPHISMS OF VITAMIN D RECEPTOR AND VITAMIN D BINDING PROTEIN (VDBP), BUT NOT VITAMIN D AND VDBP SERUM LEVELS, MAY AFFECT SUSCEPTIBILITY TO VIRAL INFECTIONS IN INFANCY (ID 1255)

Session Name
0773 - Virtual Poster Discussion Session (ID 129)
My link to connect
https://us05web.zoom.us/j/*******270?pwd=S2NBUE02cjNaZ2tnMmI1dWhGQVJLZz09
Availability (Date and Time)
12/04/2022 12:00-16:00