Alberto Muñoz (Spain)

HOSPITAL 12 DE OCTUBRE PAEDIATRICS
DATE OF BIRTH: 12/08/1993, Utrera (Spain). NATIONALITY: Spanish. I obtained the Medical Degree at Sevilla University (Spain) in 2017. I am currently a fourth year resident at 12 de Octubre University Hospital in Madrid (Spain), specializing in Pediatric Infectious Diseases. I became a Young ESPID Member in January 2022. I took part in previous EPID Online Congresses (2020 and 2021) and attended the Walter Marget Workshop at ESPID 2021. I have published several articles in Spanish scientific magazines and collaborate in research projects in Kawasaki disease and multisystem inflammatory syndrome in children. I took part in national pediatric congresses as assistant and speaker. My native language is Spanish and I also speak English (Cambridge B2 level) and French. My main personal interests are sport (athletics federated competition in track & field and cross country with participations in U20, U23 and college national championships), classic and contemporary cinema, English literature and travelling.

Author Of 1 Presentation

 Conference Calendar

EPIDEMIOLOGY AND OUTCOMES OF GRAM-NEGATIVE BACTEREMIA IN A TERTIARY UNIVERSITY HOSPITAL IN MADRID, SPAIN (2018-2020).

Date
Wed, 11.05.2022
Session Time
13:40 - 15:10
Session Type
Parallel Symposium
Session Name
0375 - PARALLEL SYMPOSIUM: Treatment Of MDR Gram (-) Infections in Children - Prevention is Best (ID 57)
Room
NIKOS SKALKOTAS HALL
Presenter
Lecture Time
14:47 - 14:57

Abstract

Backgrounds:

Gram-negative bacteremia (GNB) is associated with a significant rate of morbidity and mortality in adults. Moreover, resistances to antibiotics are increasingly described in surveillance reports. However, the epidemiology and outcomes of GNB in children are not well known. We aimed to analyze GNB bacteremia in pediatric patients in a tertiary hospital over a three years period.

Methods

A retrospective, observational study of bacteremia episodes caused by Enterobacteriaceae or non-fermentative GNB in pediatric patients between January of 2018 and December 2020 in a Tertiary Hospital from Madrid, Spain, was carried out through microbiology charts and clinical records. Demography, comorbidities, risk factors and infection characteristics were recorded, and bacterial strain and antibiotic resistance were registered. Three primary endpoints were defined: mortality, bacteremia persistence and recurrence. A statistical analysis was applied to assess differences in these outcomes according to the risk factors. A multivariable logistic regression analysis was used to assess the association between bacteria resistance and mortality.

Results:

One hundred eighteen cases of GNB in one hundred and seven patients were included. The characteristics of the patients are shown in Table 1. In fifty-three cases (44.9%) GNB presented resistance to at least one group of antibiotic and in nine (7.6%) were multidrug-resistant (Table 1). The incidence of resistance rates by years were stable. Indwelling urinary catheterization was a risk factor associated to mortality [OR 3.48 (1.20-10.6)] and parenteral nutrition was related to persistent bacteremia [OR 7.69 (1.1-209)]. No relation between drug resistance and mortality was observed in multivariable analysis.

img bgn.jpg

Conclusions/Learning Points:

GNB represented an important problem in our institution, mainly related to neonatal intensive care and heart surgery. Antibiotic resistance was common. Patients that carried invasive care devices presented higher rates of bacteremia persistence and mortality.

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Presenter of 1 Presentation

 Conference Calendar

EPIDEMIOLOGY AND OUTCOMES OF GRAM-NEGATIVE BACTEREMIA IN A TERTIARY UNIVERSITY HOSPITAL IN MADRID, SPAIN (2018-2020).

Date
Wed, 11.05.2022
Session Time
13:40 - 15:10
Session Type
Parallel Symposium
Session Name
0375 - PARALLEL SYMPOSIUM: Treatment Of MDR Gram (-) Infections in Children - Prevention is Best (ID 57)
Room
NIKOS SKALKOTAS HALL
Presenter
Lecture Time
14:47 - 14:57

Abstract

Backgrounds:

Gram-negative bacteremia (GNB) is associated with a significant rate of morbidity and mortality in adults. Moreover, resistances to antibiotics are increasingly described in surveillance reports. However, the epidemiology and outcomes of GNB in children are not well known. We aimed to analyze GNB bacteremia in pediatric patients in a tertiary hospital over a three years period.

Methods

A retrospective, observational study of bacteremia episodes caused by Enterobacteriaceae or non-fermentative GNB in pediatric patients between January of 2018 and December 2020 in a Tertiary Hospital from Madrid, Spain, was carried out through microbiology charts and clinical records. Demography, comorbidities, risk factors and infection characteristics were recorded, and bacterial strain and antibiotic resistance were registered. Three primary endpoints were defined: mortality, bacteremia persistence and recurrence. A statistical analysis was applied to assess differences in these outcomes according to the risk factors. A multivariable logistic regression analysis was used to assess the association between bacteria resistance and mortality.

Results:

One hundred eighteen cases of GNB in one hundred and seven patients were included. The characteristics of the patients are shown in Table 1. In fifty-three cases (44.9%) GNB presented resistance to at least one group of antibiotic and in nine (7.6%) were multidrug-resistant (Table 1). The incidence of resistance rates by years were stable. Indwelling urinary catheterization was a risk factor associated to mortality [OR 3.48 (1.20-10.6)] and parenteral nutrition was related to persistent bacteremia [OR 7.69 (1.1-209)]. No relation between drug resistance and mortality was observed in multivariable analysis.

img bgn.jpg

Conclusions/Learning Points:

GNB represented an important problem in our institution, mainly related to neonatal intensive care and heart surgery. Antibiotic resistance was common. Patients that carried invasive care devices presented higher rates of bacteremia persistence and mortality.

Hide