Shogo Otake (Japan)
Kobe Children’s Hospital Division of Infectious Disease, Department of PediatricsPresenter of 1 Presentation
EFFECTS OF A NUDGE-BASED ANTIMICROBIAL STEWARDSHIP PROGRAM IN A PEDIATRIC PRIMARY EMERGENCY MEDICAL CENTER (ID 92)
Abstract
Background
Outpatient medical facilities tend to have high antimicrobial prescription rates, and are therefore major targets for antimicrobial stewardship programs. Previous studies have shown high rates of unnecessary antimicrobial prescriptions in outpatient settings (e.g., emergency departments, urgent care clinics, retail clinics, and medical centers). Pediatric primary emergency medical centers in Japan have difficulties in implementing conventional antimicrobial stewardship programs due to the low continuity of stewardship. Accordingly, there is a need to develop effective antimicrobial stewardship program models for these facilities.
Methods
We conducted a single-center, quasi-experimental study to evaluate the effects of a nudge-based antimicrobial stewardship program in reducing unnecessary third-generation cephalosporin prescriptions in a pediatric primary emergency care center. The implemented antimicrobial stewardship program utilizes monthly newsletters that report current antimicrobial use patterns and prescribing targets. We compared the monthly third-generation cephalosporin prescription numbers and proportions of unnecessary prescriptions before and after the program was implemented. The trends in third-generation cephalosporin prescriptions were examined using an interrupted time-series analysis.
Results
The numbers of patients before and after program implementation were 129,156 and 28,834, respectively. The number of unnecessary third-generation cephalosporin prescriptions decreased by 67.2% in the year after program implementation. The interrupted time-series analysis showed that the program was significantly associated with a reduction in third-generation cephalosporin prescriptions (regression coefficient: -0.58, P< 0.001).
Conclusions
The nudge-based antimicrobial stewardship program was effective in reducing third-generation cephalosporin use in a Japanese pediatric primary emergency care center. This simple and inexpensive approach may have applications in other outpatient facilities.