Kasper Adelborg (Denmark)
Aarhus University Hospital Department of Clinical EpidemiologyAuthor Of 1 Presentation
STROKE RECURRENCE IN DENMARK: RISK AND MORTALITY
Abstract
Background And Aims
Knowledge on the risk and prognosis of stroke recurrence is limited. We examined risks of stroke recurrence and mortality after first and recurrent stroke.
Methods
Danish patients (≥18 years) with a first-time ischemic stroke (IS; n = 105,527) or intracerebral hemorrhage (ICH; n = 13,387) during 2004–2018 were identified from the Danish Stroke Registry and the Danish National Patient Registry. Using competing risk methods, we computed absolute risks, risk differences, and odds ratios of stroke recurrence separately for each stroke subtype and within patient subgroups. Mortality was assessed with the Kaplan-Meier estimator.
Results
The 1-year and 10-year risks of recurrence were 4% and 13% for IS and 2% and 7% for ICH. For IS, the risk increased marginally with age and was higher for men than for women, for milder first-time stroke than for more severe, and for obese than for normal weight patients. Essen risk scores predicted recurrence in a dose-response manner. For ICH, risks were similar between sexes and did not increase with body mass index and Essen risk score. For IS, the 1-year and 10-year risks of mortality were 17% and 56% after first-time stroke and 22% and 69% after recurrent stroke; corresponding estimates for ICH were 37% and 69% after a first-time event and 41% and 82% after a recurrent event.
Conclusions
The risk of stroke recurrence was substantial, especially after IS, but the risk varied among subgroups. The risk of mortality was higher after a recurrent than first-time stroke.