Found 1 Presentation For Request "1319p"
1319P - Interdependence of KRAS and TP53 mutations in predicting benefit from immune checkpoint inhibitor (ICI) in non-squamous NSCLC
- Xiaoyan Li (Beijing, China)
Abstract
Background
Genetic aberrations in
Methods
We retrospectively collected the clinical and mutational data of the patients with
Results
In the overall population, higher ORR was linked with Pooled estimate
Variable ORR PFS RR (95%CI) P HR (95%CI) P 0.82 (0.56-1.19) 0.295 1.53 (0.92-2.56) 0.104 0.91 (0.65-1.27) 0.566 1.28 (0.61-2.71) 0.518 1.04 (0.60-1.79) 0.885
Conclusions
Meta-cohort analysis involving 8 cohorts of 1129 patients demonstrate the interdependence of
Legal entity responsible for the study
Lin Li.
Funding
National Natural Science Foundation of China (81974361 to Xiaoyan Li) and CAMS Innovation Fund for Medical Sciences (2018-I2M-1-002 to Lin Li).
Disclosure
All authors have declared no conflicts of interest.