Our study was carried out with 1cc peripheral blood samples taken from premature babies born in the 35-38 week range. The patient group consisted of 32 patients who were followed up at the Erciyes University Ophthalmology Department's retinopathy of prematurity (ROP).
| Immature monocyte cells and endothelial stem cells were characterized by flow cytometry. The following markers CD34+, CD31+, CD133+, CD116+, CD144+, CD146+, CD309+ cell surface expression levels were measured |
| It was found that CD146, CD309, CD133 markers whose surface receptor expression levels were expressed at a higher level in the patient group than in the control group. In addition, the expression levels of these markers were determined on the day of diagnosis and 15 days after diagnosis. The level of expression at the time of diagnosis was higher than the level of measurement after diagnosis and treatment. Decreased surface receptor expression levels were observed after treatment. |
| It was found that CD146, CD309, CD133 markers on monocytes were useful marker for the clinical follow up of ROP patients. |