Organised by the EPA Section on Old Age Psychiatry. Apathy is a symptom that can be encountered in various psychiatric (affective disorder, psychosis), neurological (neuro-cognitive disorder such as Alzheimer disease, frontotemporal dementia or Parkinson’s disease) and also general affections (for example stroke, cancers, hypothyroidism). It is frequent and associated with both poor health outcomes and the caregiver burden. It is not described in the international classification of mental disorders, yet a growing body of literature strengthen apathy as a strong component of neuropsychiatric disorders. It is currently understood as a trans-nosographic and multi-dimensional concept including reduced goal-oriented behaviors, cognitions and social-interactions. It has relied for a long-time on motivation, which, although difficult to define and to quantify, remains a psychological construct of interest. During this course, we will address i) the diagnosis pathway starting with apathy in light of the clinical context and of the concurrent symptoms ii) a clear strategy to lead a clinical examination of apathy (including the caregiver burden assessment associated with apathy) iii) the different screening tools and more advanced scales to quantify apathy iv) the most robust data related to the pathophysiological mechanisms underlying apathy and v) the possible psychopharmacological and psychotherapeutics available at hand. To this, we will provide clinical vignettes and enhance experience sharing using small groups discussion interactions. Role play will be performed so that participants can integrate the basics apathy clinical examination. Participants will be able to provide questions throughout the course and regular tests will be carried out to ensure appropriate understandings of the topic.