D. Papola, Italy

University of Verona Department of Neuroscience, Biomedicine and Movement Sciences
D. Papola is a psychiatrist and PhD Candidate at WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation - Department of Neuroscience, University of Verona. He is currently involved in research projects regarding: - the evaluation of efficacy and acceptability of psychotropic drugs and psychotherapy through designing and performing epidemiological, observational and experimental studies, as well as systematic reviews, meta-analyses and umbrella reviews; - the evaluation of the efficacy and acceptability of pharmacological and psychosocial interventions for the treatment of mental health disorders in people with severe medical conditions; - global mental heath.

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 Conference Calendar
Oral Communications (ID 1110) AS13. Epidemiology and Social Psychiatry

O141 - Which psychotherapy is effective in panic disorder? Findings and reflections from a systematic network meta-analysis.

Session Name
Oral Communications (ID 1110)
Date
Sat, 10.04.2021
Session Time
07:00 - 21:00
Room
On Demand
Lecture Time
04:12 - 04:24
Presenter

ABSTRACT

Introduction

Panic disorder is among the most prevalent anxiety diseases. Although psychotherapy is recommended as first-line treatment for panic disorder, little is known about the relative efficacy of different types of psychotherapies.

Objectives

To evaluate the effectiveness and acceptability of different types of psychotherapies for adults suffering from panic disorder, with or without agoraphobia.

Methods

We are conducting a systematic network meta-analysis of randomized controlled trials examining panic disorder. A comprehensive search was performed to identify relevant studies. The primary efficacy outcome is anxiety symptoms at study endpoint. The primary acceptability outcome is all-cause trial discontinuation at endpoint. Pairwise and network meta-analysis will be conducted. We are considering any kind of psychotherapy delivered by any therapist, as long as they were trained to deliver the therapy, or as self-help.

Results

To date we have identified 126 panic disorder and agoraphobia trials. The publication time span ranges from 1968 to 2020. We are now extracting data to provide an overview of the included study characteristics. The statistical analysis will be conducted between December 2020 and January 2021, and its results presented for the first time at the forthcoming 2021 EPA congress.

Conclusions

126 trials on psychotherapy for panic disorders in adults are available. Because of this huge body of knowledge, it is important that the results of these studies are summarized using network meta-analytic techniques. The findings of this study will guide future research as knowledge gaps will be easily identified. Moreover, policymakers will have the opportunity to use this summarized knowledge to inform evidence-based decision making.

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