106P - The value of adjuvant chemotherapy in patients with resected stage IB solid predominant and solid non-predominant lung adenocarcinoma
- Shuhui Cao (CN)
- Jianlin Xu (CN)
- Hua Zhong (CN)
- Shuhui Cao (CN)
Abstract
Background
The adjuvant chemotherapy(ACT) of stage IB lung adenocarcinoma remain controversial, and solid ingredients were supposed to be connected to the poor survival. We are intended to explore the benefits adjuvant chemotherapy made on patients in IB with solid ingredients.
Methods
a number of 334 completely resected patients with lung adenocarcinoma in stage IB from 2006 to 2015 were reviewed. All the pathological slides were evaluated with solid ingredients composed.
Results
Our data showed that although disease-free survival (DFS)(p = 0.661) and overall survival (OS)(p = 0.130) were not significantly different in solid growth pattern with or without ACT, patients with solid predominant patterns tend to have longer DFS [hazard ratio (HR) 0.403, p = 0.021)]and OS (HR 0.286, p = 0.009) with ACT. In patients with solid non-predominant patterns, receiving ACT had little influence in DFS(p = 0.231) and OS (p = 0.611).
Conclusions
the solid predominant pattern in postoperative patients of stage IB could benefit from adjuvant, and solid non-predominant pattern couldn't.
Legal entity responsible for the study
Shanghai chest hospital
Funding
Has not received any funding
Disclosure
All authors have declared no conflicts of interest.
