Sergio Harari is chief of the Department of medicine and director of the Division of Internal Medicine at San Giuseppe Hospital, Milan. The Division is a national reference for the diagnosis and care of rare pulmonary diseases, vascular and interstitial. Prof Harari is associate professor of Internal Medicine at the University of Milan Prof. Harari introduced lung transplantation in Italy and for ten years was director of the first Italian program in advance respiratory failure and lung transplantation. His fields of interest cover rare pulmonary diseases (IPF, LAM, Pulmonary Langerhans’ cell histiocytosis, Pulmonary hypertension, etc.) and clinical research on orphan drugs. In addition, Prof. Harari is author of numerous publications in international peer-reviewed journals and specialty books and is Section Editor of the European Respiratory Review and Associate Editor of European Respiratory Journal, of the International Journal of Tuberculosis and other lung disease and of Sarcoidosis.

Professor Derralynn Hughes is Clinical Director of Research and Innovation at the Royal Free London NHS Foundation Trust, Co-clinical director of the North Central London Cancer Alliance and Professor of Experimental Haematology at the University College London, UK. She has clinical responsibilities in the area of Haematology and Lysosomal Storage Disorders and is chair of the anaemia clinical practice group. She directs the research programme in the LSD unit research laboratory where interests include understanding the pathophysiology of phenotypic heterogeneity in Fabry Disease and bone related pathology in Gaucher disease and malignancy. Prof Hughes is Principle Investigator of a number of clinical trials examining the efficacy of new agents in the treatment of Gaucher, Fabry, Pompe and MPS disorders. A particular interest relates to the clinical and biological effects of Fabry disease in women. She is an author of over 150 papers in the area of macrophage biology and Lysosomal Storage Disorders.