Bruno Antunes (Portugal)

Hospital da Luz Lisboa GCL-PPCIRA

Author of 1 Presentation

IMPACT OF AN ANTIMICROBIAL STEWARDSHIP PROGRAMME ON THE PRESCRIPTION OF CARBAPENEMS AND QUINOLONES

Date
Fri, 19.03.2021
Session Time
10:00 - 11:00
Room
Hall C
Lecture Time
10:35 - 10:42

Abstract

Background and Aims

An Antimicrobial Stewardship Programme (AMSP) has been implemented in our hospital in the second semester of 2017. One of the goals was the reduction of the consumption of carbapenems and quinolones. The evolution of the consumption of these drugs during the three years after implementing this programme has been evaluated.

Methods

We analysed the prescriptions of carbapenems and quinolones among inpatients between July 1st 2017 and March 31st 2020. The clinician reviewed each prescription and intervened, when necessary, directly with the prescriber. Antimicrobial consumption was calculated following the Nordic Council definition (2018 update) for the daily defined dose.

Results

In the first year we identified 234 (35.0%) non-conform prescriptions. Recommendations were issued in 108 cases; 83.3% were accepted. In the second year we identified 284 (34.5%) non-conform prescriptions. Recommendations were issued in 215 cases, of which 94.0% were accepted. The consumption of quinolones and carbapenems was reduced, respectively, by 18.0% and 8.6% in the first year and by 55.7% and 10.3% in the second year. Our preliminary data for the third year shows 24.3% non-conform prescriptions. Recommendations have been issued in 278 cases; 98.2% were accepted. The consumption of carbapenems and quinolones is predicted to decrease even further by 25.8% and 8.2%, respectively.

Conclusions

We found a reduction in the consumption of quinolones and carbapenems and an increase in compliance with the AMSP recommendations, reflecting a better education for prescription. This favours a more adequate use of antimicrobials, with lesser predisposal to the development of resistance.

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