Professor Derralynn Hughes is Clinical Director of Research and Innovation at the Royal Free London NHS Foundation Trust, Co-clinical director of the North Central London Cancer Alliance and Professor of Experimental Haematology at the University College London, UK. She has clinical responsibilities in the area of Haematology and Lysosomal Storage Disorders and is chair of the anaemia clinical practice group. She directs the research programme in the LSD unit research laboratory where interests include understanding the pathophysiology of phenotypic heterogeneity in Fabry Disease and bone related pathology in Gaucher disease and malignancy. Prof Hughes is Principle Investigator of a number of clinical trials examining the efficacy of new agents in the treatment of Gaucher, Fabry, Pompe and MPS disorders. A particular interest relates to the clinical and biological effects of Fabry disease in women. She is an author of over 150 papers in the area of macrophage biology and Lysosomal Storage Disorders.