Welcome to the EAS 2023 Interactive Program

The congress will officially run on CET time zone (Central European Time)

Displaying One Session

Session Type
Industry Session
Date
Mon, 22.05.2023
Session Time
14:45 - 15:30
Room
Hall: Rudolf Schönheimer
Session Description
CETP-inhibition for Cardiovascular Disease Prevention and Beyond - Industry Sponsored Session by New Amsterdam Pharma. The main role of cholesteryl ester transfer protein (CETP) is the transfer of cholesteryl esters and triglycerides between high-density lipoprotein (HDL) particles and triglyceride-rich and low-density lipoprotein (LDL) particles. There is a long history of investigations regarding the inhibition of CETP as a target for reducing major adverse cardiovascular events. Initially, the potential effect on cardiovascular events of CETP inhibitors was hypothesized to be mediated by their ability to increase HDL cholesterol, but, based on evidence from anacetrapib and the newest CETP inhibitor, obicetrapib, it is now understood to be primarily due to reducing LDL cholesterol and apolipoprotein B. Additionally, evidence is also mounting that other roles of HDL, including its promotion of cholesterol efflux, as well as its apolipoprotein composition and anti-inflammatory, anti-oxidative, and anti-diabetic properties, play important roles in several diseases beyond cardiovascular disease. This program will describe evidence for CETP to reduce LDL-C, Apo B and MACE in addition to the latest biological evidence regarding the relationship between HDL and CETP inhibition for Alzheimer’s disease, diabetes mellitus, sepsis, and AMD.

Opening Comments (ID 1646)

Session Type
Industry Session
Date
Mon, 22.05.2023
Session Time
14:45 - 15:30
Room
Hall: Rudolf Schönheimer
Lecture Time
14:45 - 14:47

CETP-inhibition for Cardiovascular Disease Prevention and Beyond (ID 1647)

Session Type
Industry Session
Date
Mon, 22.05.2023
Session Time
14:45 - 15:30
Room
Hall: Rudolf Schönheimer
Lecture Time
14:47 - 15:15

Moderator Led Q&A (ID 1648)

Session Type
Industry Session
Date
Mon, 22.05.2023
Session Time
14:45 - 15:30
Room
Hall: Rudolf Schönheimer
Lecture Time
15:15 - 15:30