Chantal Mathieu, Belgium

University Hospitals Leuven - KU Leuven Endocrinology
Chantal Mathieu is a physician-scientist who has contributed to the field of diabetes and endocrinology through basic and clinical research. Her work in animal models of type 1 diabetes established 1,25-dihydroxyvitamin D3 as an immune modulator and demonstrated the potential of Lactococcus lactis as a carrier tool for peptides and proteins, which became the basis for a worldwide clinical trial in people with newly diagnosed type 1 diabetes. Her research group was amongst the first to demonstrate the relevance of post-translational modifications of beta-cell peptides and proteins in autoantigen generation in murine and human type 1 diabetes. Prof. Mathieu’s clinical work involving new products and treatment paradigms in diabetes, such as new insulins, adjunct therapies and diagnosis of gestational diabetes as well as her educational skills have made her a prominent speaker in international fora. She has promoted shared-care, positioning of diabetes education and reimbursement of novel technologies. Prof. Mathieu is co-author of several consensus papers, including the 2018-19 ADA/EASD Consensus on glucose lowering therapies in type 2 diabetes. Prof. Mathieu leads the INNODIA project and established its Patient Advisory Committee. Prof. Mathieu is also (senior) vice-president of EASD, Chair of postgraduate education and Chair of the European Diabetes Forum.

Presenter of 10 Presentations

INDUSTRY SESSION

Meeting close

PARALLEL SESSION

Introducing INNODIA & INNODIA HARVEST

Abstract

Abstract Body

INNODIA - Translational approaches to disease modifying therapy of type 1 diabetes: An innovative approach towards understanding and arresting Type 1 diabetes

The overall objective of INNODIA is to advance in a decisive way how we predict, stage, evaluate and prevent the onset and progression of type 1 diabetes (T1D). We are achieving this by creating novel tools, such as biomarkers, disease models and clinical trial paradigms. These tools allow us to distinguish and understand at the cellular and molecular level distinctive paths of ontogeny and progression in this heterogeneous disease, thus impacting on the future management of T1D patients and at risk individuals. We have established an interdisciplinary network of clinical and basic scientists, who are leading experts in the field of T1D in Europe, with complementary expertise from the areas of immunology, b-cell biology, biomarker research and T1D therapy, joining forces in a coordinated fashion between academic and industry partners, two foundations, as well as with patients with T1D and their families.

INNODIA follows over 600 people with newly diagnosed T1D with intensive biomarker measures. Over 4000 first degree family members of people with T1D have been screened of whom close to 300 have been found to have autoantibodies against the b-cell. Over 250 of these autoantibody-positive individuals accepted to be followed up intensively for biomarker research.

Since November 2020 INNODIA has initiated 4 clinical trials in people with newly diagnosed T1D (ranging from 5y to 45y). All trials are based on the INNODIA Masterprotocol follow up scheme and are using intensive CGM monitoring as a tool for glucose follow up.

More information on INNODIA and our clinical trials can be found on www.innodia.eu .

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INDUSTRY SESSION

Welcome and Introductions

INDUSTRY SESSION

Welcome and introduction

INDUSTRY SESSION

What’s next? Exploring the potential of once-weekly basal insulin

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Closing Remarks

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The Role of Technology in Type 1 Diabetes Beyond the Pandemic

Moderator of 3 Sessions

INDUSTRY SESSION
Date
Thu, 03.06.2021
Session Type
INDUSTRY SESSION
Session Time
17:15 - 18:45
Room
Hall F
Session Description

Insulin Innovation: Celebrating 100 years and beyond - Industry Symposium Supported by Novo Nordisk

Session description - This symposium will celebrate a century of insulin by reflecting on 100 years of innovation and looking into the future of insulin therapies. The aims for the symposium are to highlight the major advances in insulin innovation over the past century, the remaining challenges, and the future landscape of potential insulin therapies. World-renowned diabetes experts will take attendees on a voyage beginning with the history of the discovery and development of insulin and the early days of insulin research. They will guide the audience through the latest clinical evidence supporting the use of once-weekly basal insulin in diabetes. Finally, they will transport the audience into the future with an exciting preview of the prospective landscape of insulin and other therapies for diabetes. There will be opportunities for attendees to engage directly through polling questions and to ask questions throughout the session, which will be answered during a live panel discussion.

INDUSTRY SESSION
Date
Wed, 02.06.2021
Session Type
INDUSTRY SESSION
Session Time
17:00 - 18:30
Room
Hall A
Session Description

MiniMed™ 780G System: Improving Clinical Outcomes while Reducing Diabetes Management Burden - Industry Symposium Supported by Medtronic International Trading Sàrl

Session description - Innovation of technology in type 1 diabetes has transformed the therapy and significantly improved both clinical and patient related outcomes. In this symposium, the most recent data on the transformation brought by the introduction of automated insulin delivery system - the MiniMed™ 780G system-, on goals obtainment in real world will be presented. The opportunities brought by these to onboard a wider population of people with diabetes, even those without extensive exposure to technology, will be demonstrated. Further innovation toward extending infusion sets wear to 7 days, and its performance with automated insulin delivery system will be presented, as an additional step toward improving users’ experience. A look toward the future innovation will be offered by the leaders of Medtronic R&D

INDUSTRY SESSION
Date
Thu, 03.06.2021
Session Type
INDUSTRY SESSION
Session Time
20:30 - 21:30
Room
Hall E
Session Description

Introducing Tempo: A Connected Insulin Pen to Simplify Diabetes Management - Industry Symposium Supported by Eli Lilly

Session description - This symposium will introduce Tempo™, a Personalized Diabetes Management System from Eli Lilly, that integrates insulin dosing data with technology to help simplify diabetes management.   Digital health technologies can help improve patient data visibility, physician-patient collaboration, clinical decision-making, and patient self-management, ultimately leading to better outcomes.   Faculty will discuss the complexities of insulin management, and how insulin dosing data may help facilitate communication between you and the people you treat.  Automating insulin dosing data may help:  

• Gain an understanding of their management patterns

• Stay informed between office visits

• Feel empowered to engage in shared decision-making

The Tempo Smart Button™ (pending CE mark) attaches to a Tempo Pen™ prefilled with Abasaglar, Humalog, or Lyumjev insulin.  Data from the Tempo System will integrate with commercially available software. The Tempo Smart Button is intended to reliably store and transmit insulin dosing data to a compatible app.  Tempo provides a comprehensive view of how people manage their insulin day-to-day.  Adding insulin dosing data to other data related to your patients’ insulin therapy (e.g., blood glucose, carbohydrate intake) may help inform treatment decisions. This program is for all healthcare professionals treating people with diabetes on multiple daily injections of mealtime insulin.

The materials for Tempo Pen™ contained in this virtual symposium are approved for use only in EU and UK. The Tempo Smart Button™ is pending CE mark. Prescribing information may vary depending on local approval in each country. Therefore, before prescribing any product, always refer to local materials such as the prescribing information and/or the Summary of Product Characteristics (SPC).