Marco Marigliano, Italy
Pediatric Diabetes and Metabolic Disorders Unit, Regional Center for Pediatric Diabetes, University City Hospital of Verona Dep.Surgery, Dentistry, Paediatrics and Gynaecology, University of Verona.Presenter of 1 Presentation
SWITCHING FROM BASAL-IQ TO CONTROL-IQ TECHNOLOGY IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES: ONE WEEK IS ENOUGH TO IMPROVE TIME IN RANGE.
- Marco Marigliano, Italy
- Andrea E. Scaramuzza, Italy
- Riccardo Bonfanti, Italy
- Rosaria Gesuita, Italy
- Sara Giorda, Italy
- Lorenzo Lenzi, Italy
- Monica Marino, Italy
- Barbara Piccini, Italy
- Ivana Rabbone, Italy
- Andrea Rigamonti, Italy
- Riccardo Schiaffini, Italy
- Sonia Toni, Italy
- Claudio Maffeis, Italy
- Valentino Cherubini, Italy
- Virtual Camp Study Group, Italy
Abstract
Background and Aims
In people with Type 1 Diabetes (T1D) the percentage of time in Range (TIR), 70-180 mg/dL, is now recognized as the most effective glucometrics together with HbA1c. The aim of this study was to analyze the early effect on TIR changes after switching from Tandem Basal-IQ to Control-IQ technology in a group of children and adolescents with T1D.
Methods
Children and adolescents from 19 Italian centers have been recruited. After a standard educational program, the enrolled patients updated pumps software from Basal-IQ to Control-IQ. Differences in TIR one week (excluding the day of the update) and three weeks before and after the update were analyzed. TIR values were summarized using median and interquartile range (IQR) and compared by Wilcoxon sign-rank test. Median differences in TIR and 95%CI were used.
Results
TIR data of 43 youths (53.5% females, median age 15y, diabetes duration 10y) were analyzed. After upgrading to Control-IQ technology, TIR significantly improved, starting after the first week [median (IQR)], 75% (70;82) vs 67% (53;73), p<0.001, and keeping steady for the whole 3-week observation: 76% (69;82) vs 65% (55;73), p<0.001 (Figure 1). Furthermore, with Control-IQ algorithm, there was a lower interindividual variability as shown by the reduced differences in the IQR.
Conclusions
A significant increase in TIR is already evident after the first week with Tandem t:slim Control-IQ technology and this improvement is kept in the following weeks of observation.